Special Issue "Phage-Bacteria Interplay in Health and Disease"
Deadline for manuscript submissions: 31 October 2021.
Interests: phage–host interactions; phage-borne enzymes; biofilm; alternative antibacterial therapies
Interests: host–pathogen interplay; outer membrane vesicles; innate immunity; inflammation; cross-reactive antibodies; Moraxella catarrhalis
Bacteriophages are obligatory parasites propagating in bacterial hosts propagating in a lytic or lysogenic cycle. Phages are the most abundant biological particles in the world, being responsible for: (i) dissolved and particulate organic matter circulation via host cell lysis, (ii) regulation and biodiversity of populations by reducing the number of dominating bacteria, (iii) horizontal gene transfer (HGT) via transduction, or indirectly via transformation of bacterial DNA released during cell lysis, and finally, (iv) lysogenic conversion by temperate phages. Therefore, phages greatly affect a microbial diversification as an integral part of each ecological niche, including the human body. The tremendous dynamics of phage–host interactions results in the continuous flow of genetic material, which drives the co-evolution of both entities.
In this Special Issue, we are looking for reports and reviews of the most current findings on phage role in the microbiome in health and disease. We welcome the submission of Original Research, Reviews, and Mini-Reviews covering, but not limited to, the following topics:
- How phages affect the regulation and functioning of human/mammal microbial ecosystems as the consequence of specific and non-specific virus–bacteria interactions, including the shaping of microbial communities, the behavior and virulence of bacteria, as well as advantages versus drawbacks of phage-induced alterations;
- How can the mechanisms of bacterial defense against phages drive the outcome of the disease/infection? This includes (i) active defense (receptor modification, CRISPR/Cas, R-M system, etc.), (ii) passive defense (OMVs release, secondary metabolites release), and (iii) the susceptibility of phage mutants/altered bacteria to host immune response;
- Bacteriophages as human immune modulators of innate and adaptive immunity as well as human viral pathogens.
Prof. Dr. Zuzanna Drulis-Kawa
Dr. Daria Augustyniak
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Phage–bacteria interaction
- Phage–host interaction
- Phage resistance
- Microbiota and phagobiota interactions
- Immune response to phage presence
- Phage–bacteria co-evolution
- Phage–bacterial infection networks