Special Issue "Applications of CRISPR Technology in Virology 2018"
A special issue of Viruses (ISSN 1999-4915).
Deadline for manuscript submissions: closed (31 October 2018).
Interests: oncogenic viruses; innate antiviral response
Precision genome engineering by CRISPR is a game-changing technology that promises to revolutionize virology and the treatment of viral diseases. CRISPR-mediated knock-in and knock-out of viral and cellular genes have been most revealing in the study of viral pathogenesis. CRISPR-based genome-wide screens, viral delivery systems for CRISPR and other CRISPR-based enabling tools including those in live cell imaging, viral disease modeling and treatment have also come of age. The applications of CRISPR technology in virology are far-reaching. The CRISPR revolution will reach beyond the research lab. In this Special Issue of Viruses we look to assemble a timely collection of research papers and reviews focusing on applications of CRISPR technology in virology. It is hoped that it will provide an update on this emerging field and serve as a reference and guide to virologists who are and will be using CRISPR in their research. The highlights will be on cutting-edge CRISPR technologies and their applications in various fields of virology such as viral reverse genetics; the study of viral entry, viral-host interaction, viral pathogenesis and cellular response to viral infection; viral immunology; as well as design and development of vaccines and antivirals. Topics of special interest may include viral delivery systems for CRISPR; functional screening for host restriction and dependency factors using CRISPR; antiviral CRISPR; CRISPR for viral disease modeling and target discovery; CRISPR in virus-infected cells and model organisms; as well as safety issues, such as off-target CRISPR editing in virus-infected cells.
Prof. Dong-Yan Jin
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Precision genome editing
- CRISPR/Cas9 system
- CRISPR screen
- Reverse genetics
- Virus-host interaction
- Host restriction factors
- Host dependency factors
- Viral vectors; Vaccines
- Antiviral agents