Nuclear Receptors as Regulators of Immunity

Dear Colleagues,

Nuclear receptors are ligand-regulated transcription factors involved in several physiological processes such as lipid and glucose metabolism, development, circadian rhythm and immunity. Notably, several nuclear receptors, including the glucocorticoid receptor (GR), retinoic acid receptors (RARs), peroxisome proliferator-activated receptors (PPARs), Rev-Erbs, RAR-related orphan receptors (RORs) and liver X receptors (LXRs) have been shown to play critical functions in the immune response. The identification of nuclear receptors as immune regulators and the development of synthetic ligands targeting these nuclear receptors open up new perspectives for treating immune diseases. In this Special Issue, we are pleased to invite investigators to contribute original articles or reviews that address the relationship between nuclear receptors and immunity. Research works about the role of nuclear receptors and their ligands on immune response, as well as their association with pathological conditions, are all welcome.

Dr. Laurent L’homme
Dr. Yasmine Sebti
Guest Editors

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• Nuclear receptors
• Ligands
• Immunity
• Immune cells
• Immune diseases
• Inflammation