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Vaccines
Special Issues
COVID-19 Vaccination Coverage, Behaviors, and Interaction with Chronic Diseases
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COVID-19 Vaccination Coverage, Behaviors, and Interaction with Chronic Diseases

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "COVID-19 Vaccines and Vaccination".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 6048

Special Issue Editor

Dr. Ahmed Negida

E-Mail Website
Guest Editor
Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA
Interests: global health; public health; health disparities; global neurosurgery; global neurology; neuroscience
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Since 2019, the COVID-19 pandemic has caused 400,000 deaths around the world. Despite the public health measures introduced in 2020, the pandemic continued. Immunizing the global population against SARS-CoV-2 is the most effective way to end the current pandemic. Several COVID-19 vaccines have been developed, evaluated, and approved for roll out in the population. Clinical trials and real-life data from these vaccines confirm their general safety and efficacy in the population. The vaccines are generally safe and effective to administer to the population except for very rare side effects such as vaccine-induced thrombocytopenia, which occurs in some high-risk individuals who take adenovirus-associated vaccines. Vaccine hesitancy and inadequate vaccine coverage are major problems in the global public health community. Without a sufficient percentage of fully immunized individuals to reach herd immunity, the pandemic will be prolonged and fatal for more people; in addition, the longer the virus continues, the more likely it is to mutate and develop more virulent or infectious strains. The assessment of vaccination status worldwide and population behaviors after vaccination is important to inform public health authorities and decision makers. This Special Issue will present articles discussing vaccine coverage, vaccine roll out, population behaviors and attitudes towards vaccines, and vaccine interaction with existing chronic diseases.

Dr. Ahmed Negida
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • COVID-19
  • vaccine
  • global health
  • complications
  • interactions
  • safety

Published Papers (3 papers)

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Research

29 pages, 1371 KiB  
Article
Comparative Analysis of Primary and Monovalent Booster SARS-CoV-2 Vaccination Coverage in Adults with and without HIV in Catalonia, Spain
by Daniel Kwakye Nomah, Juliana Reyes-Urueña, Lucía Alonso, Yesika Díaz, Sergio Moreno-Fornés, Jordi Aceiton, Andreu Bruguera, Raquel Martín-Iguacel, Arkaitz Imaz, Maria del Mar Gutierrez, Ramón W. Román, Paula Suanzes, Juan Ambrosioni, Jordi Casabona, Jose M. Miro, Josep M. Llibre and the PISCIS Study Group
Vaccines 2024, 12(1), 44; https://doi.org/10.3390/vaccines12010044 - 30 Dec 2023
Viewed by 1623
Abstract
People with HIV (PWH) may be more susceptible to SARS-CoV-2 infection and worse clinical outcomes. We investigated the disparity in SARS-CoV-2 vaccination coverage between PWH and those without HIV (PWoH) in Catalonia, Spain, assessing primary and monovalent booster vaccination coverage from December 2021 [...] Read more.
People with HIV (PWH) may be more susceptible to SARS-CoV-2 infection and worse clinical outcomes. We investigated the disparity in SARS-CoV-2 vaccination coverage between PWH and those without HIV (PWoH) in Catalonia, Spain, assessing primary and monovalent booster vaccination coverage from December 2021 to July 2022. The vaccines administered were BNT162, ChAdOx1-S, mRNA-127, and Ad26.COV2.S. Using a 1:10 ratio of PWH to PWoH based on sex, age, and socioeconomic deprivation, the analysis included 201,630 individuals (183,300 PWoH and 18,330 PWH). Despite a higher prevalence of comorbidities, PWH exhibited lower rates of complete primary vaccination (78.2% vs. 81.8%, p < 0.001) but surpassed PWoH in booster coverage (68.5% vs. 63.1%, p < 0.001). Notably, complete vaccination rates were lower among PWH with CD4 <200 cells/μL, detectable HIV viremia, and migrants compared to PWoH (p < 0.001, all). However, PWH with CD4 < 200 cells/μL received more boosters (p < 0.001). In multivariable logistic regression analysis of the overall population, a prior SARS-CoV-2 diagnosis, HIV status, migrants, and mild-to-severe socioeconomic deprivation were associated with lower primary vaccination coverage, reflecting barriers to healthcare and vaccine access. However, booster vaccination was higher among PWH. Targeted interventions are needed to improve vaccine coverage and address hesitancy in vulnerable populations. Full article
(This article belongs to the Special Issue COVID-19 Vaccination Coverage, Behaviors, and Interaction with Chronic Diseases)
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26 pages, 19946 KiB  
Article
Age and Comorbidities as Risk Factors for Severe COVID-19 in Mexico, before, during and after Massive Vaccination
by Lenin Domínguez-Ramírez, Francisca Sosa-Jurado, Guadalupe Díaz-Sampayo, Itzel Solis-Tejeda, Francisco Rodríguez-Pérez, Rosana Pelayo, Gerardo Santos-López and Paulina Cortes-Hernandez
Vaccines 2023, 11(11), 1676; https://doi.org/10.3390/vaccines11111676 - 2 Nov 2023
Viewed by 1686
Abstract
During 2020–2023, Mexico had a large COVID-19 emergency with >331,000 adult deaths and one of the highest excess mortalities worldwide. Age at COVID-19 death has been lower in Mexico than in high-income countries, presumably because of the young demographics and high prevalence of [...] Read more.
During 2020–2023, Mexico had a large COVID-19 emergency with >331,000 adult deaths and one of the highest excess mortalities worldwide. Age at COVID-19 death has been lower in Mexico than in high-income countries, presumably because of the young demographics and high prevalence of chronic metabolic diseases in young and middle-aged adults. SARS-CoV-2 vaccination covered 85% of adults with at least one dose and 50% with booster(s) up to April 2022. No new vaccination efforts or updated boosters were introduced until October 2023; thus, we explored the public health impact of massive SARS-CoV-2 vaccination against ancestral strains and asked whether their real-world protection has persisted through time. We compared three periods with respect to vaccine roll-outs: before, during and after vaccine introduction in a national retrospective cohort of >7.5 million COVID-19 cases. The main findings were that after vaccination, COVID-19 mortality decreased, age at COVID-19 death increased by 5–10 years, both in populations with and without comorbidities; obesity stopped being a significant risk factor for COVID-19 death and protection against severe disease persisted for a year after boosters, including at ages 60–79 and 80+. Middle-aged adults had the highest protection from vaccines/hybrid immunity and they more than halved their proportions in COVID-19 deaths. Full article
(This article belongs to the Special Issue COVID-19 Vaccination Coverage, Behaviors, and Interaction with Chronic Diseases)
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11 pages, 251 KiB  
Article
COVID-19 Risk Perception and Adherence to Preventive Measures among Medical Students after Receiving COVID-19 Vaccination: A Multicenter Cross-Sectional Study in Egypt
by Abdullah Ashraf Hamad, Rasha Selim, Basma E. Amer, Rehab Adel Diab, Mahmoud Elazb, Eman H. Elbanna, MRGE Collaborative Group and Ahmed Negida
Vaccines 2023, 11(1), 7; https://doi.org/10.3390/vaccines11010007 - 20 Dec 2022
Cited by 2 | Viewed by 2085
Abstract
This study aimed to assess the perception of COVID-19 risk and the adherence to protective measures among medical students after vaccination. We conducted a cross-sectional survey on a convenience sample of students from all the 18 governmental medical schools in Egypt. A total [...] Read more.
This study aimed to assess the perception of COVID-19 risk and the adherence to protective measures among medical students after vaccination. We conducted a cross-sectional survey on a convenience sample of students from all the 18 governmental medical schools in Egypt. A total of 2273 students participated in the online self-administered questionnaire. Around 8 in 10 (83.2%) students were fully vaccinated, of which 17.9% received the booster dose. Only 36.9% believed that COVID-19 is serious on the individual level. The majority (73.9%) strongly or slightly agreed they may become infected after vaccination if they do not follow the preventive measures. We observed a slow decline in the perceived risk of vulnerability and susceptibility to COVID-19 infection among students in parallel to a growing perception of self-efficacy and controllability. Less than one-third (28.9%) of students showed good adherence to protective measures. However, this was lower than the previously reported adherence in the same population before vaccination. Female students, those in the first academic year, those who did not contract COVID-19 infection before, and those with a higher perception of susceptibility and perceived controllability were more likely to perform better at protective measures. Full article
(This article belongs to the Special Issue COVID-19 Vaccination Coverage, Behaviors, and Interaction with Chronic Diseases)
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