Special Issue "Application of Protein Toxins as Cell Biological and Pharmacological Tools"
A special issue of Toxins (ISSN 2072-6651).
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 18026
Interests: endocytosis; intracellular trafficking; protein toxins; lectins; glycobiology; glycosphingolipids; lipid rafts; membrane compartmentalization; intracellular delivery; membrane translocation; immunotherapy; tumor targeting
Protein toxins from bacteria and plants are a serious threat to human and animal health. However, because of their intimate interactions with host cells, they have also become valuable tools to molecularly dissect cell biological functions that range from endocytosis and intracellular trafficking to cell signaling and apoptosis. Several characteristics such as ease for biochemical handling and the robustness of phenotypes are responsible for their success as cell biological tools. The in-depth understanding of their activities has, in turn, also attracted attention to their use as pharmacological tools to manipulate cellular processes that misfunction in disease situations or that can be targeted for therapeutic intervention. Cancer immunotherapy by immunotoxins or toxin subunit-based vaccines are only some of the many possibilities for using toxins in biomedical research. In this special issue of Toxins, primary research papers and review articles are assembled that address the aspects that are summarized above. The reader is thereby provided with an up-to-date perspective on some of the most recent and dynamic contributions of toxins to fundamental cell biology and applied cellular pharmacology research.
Dr. Ludger Johannes
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- intracellular trafficking
- lipid domains
- broad spectrum inhibitors