Journal Menu► ▼ Journal Menu
Journal Browser► ▼ Journal Browser
Special Issue "Advances in The Toxicity Mechanisms of Microcystins Revealed by Omics Approaches"
Deadline for manuscript submissions: 15 May 2020.
Interests: cyanotoxins; toxicity mechanisms; proteomics; toxin genes, gene expression
Interests: cyanotoxins; ecotoxicology; exposure routes and risk assessment of cyanotoxins toxins; contamination of aquatic organisms with cyanotoxins
Special Issues and Collections in MDPI journals
Special Issue in Toxins: Proteomics and the Study of Marine Toxins: Implications for Life Sciences
Microcystins (MCs) are toxins from freshwaters and produced by cyanobacteria which are known worldwide. Given their toxicological relevance, they have already been included as one of the parameters included in drinking water legislation in many countries.
Considerable research has been conducted concerning the molecular mechanisms behind microcystins’ toxicity. Currently, it is known that microcystins are able to induce major damages in animal cells through cytotoxic and genotoxic effects leading to apoptosis, tumor promotion, and cancer. Furthermore, it has also been verified that MCs are also able to induce neurotoxic effects and provoke damages in reproductive organs, and the main molecular target in animal cells has been identified.
This Special Issue aims to bring together papers that provide new information on the molecular mechanisms underlying the toxicity of microcystins, especially those revealed by OMICS approaches (proteomics, transcriptomics, and metabolomics). Manuscripts that contribute to better understanding how MCs act in different model organisms, the respective molecular targets and the toxicity of the different MC variants, as well as on the role of protein phosphatases in the toxicity of MCs are most welcomed.
Dr. Elisabete Valério
Dr. Alexandre Campos
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- toxicity mechanisms
- gene expression
- adverse outcome pathways