Special Issue "Antibodies for Toxins: From Detection to Therapeutics"
A special issue of Toxins (ISSN 2072-6651).
Deadline for manuscript submissions: closed (31 October 2020) | Viewed by 16074
Interests: immunoassays; diagnosis; lateral flow immunoassays; ELISA; biosensors; monoclonal antibodies; immunotherapy; neutralization assays; bacterial toxins; Botulinum neurotoxins; Staphylococcus enterotoxins; Clostridium perfringens enterotoxins; plant toxins; ricin; abrin
Interests: pharmacology; bioanalysis; health technologies
Antibodies are key determinants in the immune response. In addition to their role in the host’s fight against infections and intoxications and thanks to their very high specificity and affinity for their targets, they are a privileged tool for the development of tests and detection methods, and for therapeutic applications. Thanks to their high selectivity, first applications had been in the design of highly sensitive immunoassays such as ELISA, plasmonic resonance assays, lateral-flow immunoassays, immuno-proteomics, and flow cytometry, among others. These methods allow toxin detection and measurements in environmental matrices as well as biological fluids with sensitivities down to the femtomolar range. In the therapeutic field, antibodies have been used as anti-toxins since the 19th century and are still the tools of choice in the fight against intoxication (bacterial toxins, plant toxins, etc.), for prophylactic and therapeutic purposes. Recombinant technologies may allow the new design of monoclonal antibodies to improve their efficacy and/or tolerance.
In this Special Issue “Antibodies for Toxins: From Detection to Therapeutics”, we wish to cover the most up-to-date research and review articles on antibody-based methods for the detection and diagnosis of different toxins in environmental or biological matrices and antibody-based therapies.
Dr. Stéphanie Simon
Dr. Eric Ezan
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- mass spectrometry
- flow cytometry