Omics Techniques for Toxins Research
A special issue of Toxins (ISSN 2072-6651).
Deadline for manuscript submissions: closed (31 August 2019) | Viewed by 9868
Interests: proteomics; foodborne pathogens; mechanisms of bacterial resistance; extracellular vesicles
Special Issues, Collections and Topics in MDPI journals
According to the Center for Disease Control and Prevention (CDC), antibiotic resistance is one of the biggest public health challenges of our time. Each year in the U.S., at least 2 million people get an antibiotic-resistant infection, and at least 23,000 people die (https://www.cdc.gov/drugresistance/index.html). In Europe, we are facing a similar situation. Sepsis and septic shock are frequent causes of deaths as a consequence of infection with resistant bacteria. Exotoxins of clinically relevant bacteria such as hemolysins can significantly impair organ functions.
On the other hand, there are more as 250 microbial pathogens known to cause food-borne illnesses. Accidents with food of mostly animal origin, and traditional fermented food products, have recently accompanied numerous cases that have occurred as a consequence of contaminations of fresh and processed food.
Microbial infection may also cause contamination with mycotoxins, bacteria, and other toxins in food, and sometimes in the environment. Omics methods such as proteomics, peptidomics, and metabolomics techniques are newly developed tolls that can help to solve the abovementioned problems. Genome, proteome, lipidome, and metabolome analyses of hosts and pathogens and their metabolites in combination with already established laboratory analyses provide reliable information about pathogen activities during infection, outbreaks of disease, and healing periods. Importantly, functionally relevant proteins and products of metabolism are identified in order to trace abovementioned diseases. Fast diagnosis is an additional critical point and in-vivo genomic, proteomic, and metabolomic data can be crucial to guide further functional analysis efficiently. It raises the importance of high-throughput omics analyses and the detection of toxins and other biomarkers of their action during disease progress that will be one of key points in this Special Issue.
Prof. Dr. Djuro Josic
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- bacterial toxins
- septic shock
- food poisoning
- high-throughput analyses