Application of Botulinum Toxin in Facial Diseases
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 9097
Special Issue Editors
Interests: ophthalmology; botox injection
Interests: clinical ophthalmology; eye diseases; emergency treatment
Special Issue Information
Dear Colleagues,
This Special Issue, titled “Application of Botulinum Toxin in Facial Diseases”, will explore the different applications of botulinum neurotoxin (BoNT) in facial treatment, including lacrymal and salivary glands. Since Alan Scott first used BoNT in Strabismus (1989), then in Central Cerebral Dystonias such as Essential Blepharospasm or Meige syndrome, quickly followed by the treatment of abnormal movements as hemi-facial spasm, the use of BoNT has revolutionized our therapeutic capabilities and the quality of life of these patients. This fantastic therapeutic revolution has made it possible to improve the diagnosis of rare diseases such as Blepharospasm and Meige syndrome by offering an effective and safe therapy. BoNT is also used in primary or secondary hemi-facial spasm, as well as in nerve regrowth synkinesis after facial paralysis. Technical improvements in the use of botulinum toxin not only allow us to treat inappropriate muscle contractions but also to improve facial symmetry after idiopathic or post-surgical muscular paralysis, especially after ENT carcinological surgery. Current clinical research highlights botulinum neurotoxin’s therapeutic potential beyond its traditional neuromuscular dystonic applications in managing hyper glandular production. The extension of BoNT indications in the glands also allows us to limit drooling in salivary hypersecretions and to stop an epiphora with patent or obstructed tear ducts. These indications are also very useful in Frey syndrome treatment. In more restricted indications, BoNT can be of great help in the correction of a hypertrophic scar. In patients who are fragile or cachectic, it can allow for the correction of an entropion if surgery is contraindicated. In this Special Issue, we will review the indications, injection techniques, handling of BoNT concentrations and the management of adverse effects in the context of facial treatment.
Dr. Brigitte Girard
Dr. Isabelle Larre
Dr. Juliette Delmas
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- botulinum neurotoxin
- blepharospasm
- hemifacial spasm
- ptosis
- drooling
- lacrymal gland
- salivary gland
- movement disorders
- entropion
- epiphora
- facial asymmetry correction
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
