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Toxins
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Advances in Detection and Removal of Mycotoxins in Food
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Advances in Detection and Removal of Mycotoxins in Food

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Mycotoxins".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 4860

Special Issue Editor

Prof. Dr. Xiaoyang Li

E-Mail Website
Guest Editor
School of Food Science and Technology, Nanchang University, Nanchang 330047, China
Interests: food safety; mycotoxins; determination

Special Issue Information

Dear Colleagues,

Mycotoxins are harmful substances that endanger human and animal health and threaten food safety. They are important research subjects in agriculture, food, and public health. Therefore, it is crucial to develop new technologies for detecting and removing mycotoxins from food effectively to ensure food safety. The determination and removal of trace amounts of mytoxins from complex food matrices remains a significant challenge. Recent advancements in biotechnology and nanomaterials have shown great promise in addressing this issue, enhancing the sensitivity of mycotoxin detection and achieving the efficient removal of mycotoxins from food.

This Special Issue will present novel and emerging approaches studied and developed for the determination and removal of mycotoxins from food/feed stuffs. It, therefore, welcomes experimental studies and review articles that employ state-of-the-art technologies.

Prof. Dr. Xiaoyang Li
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food safety
  • mycotoxins
  • determination
  • detoxification
  • biotechnology
  • nanomaterials

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

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Research

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15 pages, 12164 KB  
Article
Ligand Screening for Enzyme Immobilization Enables Efficient Removal of Aflatoxin B1 in Continuous Flow System
by Yujie Peng, Shenglong Mu and Jun Ge
Toxins 2026, 18(2), 95; https://doi.org/10.3390/toxins18020095 - 12 Feb 2026
Viewed by 696
Abstract
Aflatoxin B1 (AFB1) contamination is a significant issue for the safety of edible oils. Biodegradation of mycotoxins represents a green and efficient approach. However, enzymes exhibit low catalytic activity and stability under harsh conditions, leading to rapid deactivation in edible oils. Zeolitic imidazolate [...] Read more.
Aflatoxin B1 (AFB1) contamination is a significant issue for the safety of edible oils. Biodegradation of mycotoxins represents a green and efficient approach. However, enzymes exhibit low catalytic activity and stability under harsh conditions, leading to rapid deactivation in edible oils. Zeolitic imidazolate frameworks (ZIFs) possess high specific surface areas, tunable pore sizes, and excellent thermal stability. Immobilizing enzymes on ZIFs can address the problem of enzyme inactivation during application. Although the stability of the enzyme can be enhanced after immobilization, the overall enzymatic activity remains limited. To overcome the issues of low catalytic activity and poor cycling stability associated with enzymes immobilized on ZIF-8 using 2-methylimidazole (2-mIM) as the ligand, this study optimized the ZIF structure through a ligand screening strategy. Both encapsulation efficiency and cycling stability were enhanced. This research found that the activity of Lac@ZIFs(IM), which uses imidazole (IM) as the ligand, was 2.16 times that of Lac@ZIF-8. The degradation efficiency of AFB1 reached 93% within 4 h in edible oil using Lac@ZIFs(IM) as the catalyst, which was 21-fold higher than that of free laccase. Lac@ZIFs(IM) exhibited excellent activity in the continuous flow system. After 20 h of continuous reaction, the activity of Lac@ZIFs(IM) was 6.6 times that of Lac@ZIF-8. This study provides a novel approach for the efficient enzymatic degradation of mycotoxins. Full article
(This article belongs to the Special Issue Advances in Detection and Removal of Mycotoxins in Food)
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19 pages, 2140 KB  
Article
Efficacy of Dodonaea viscosa Extract and Its Chitosan-Based Nanoparticle Formulation on the Growth of Fusarium Strains and the Production of Deoxynivalenol and Moniliformin in Stored Wheat
by Hussein Ali Salman Alsahho, Sumer Horuz and Kevser Karaman
Toxins 2025, 17(11), 551; https://doi.org/10.3390/toxins17110551 - 5 Nov 2025
Viewed by 1049
Abstract
Fusarium is considered one of the most important fungi that attack plants and cause serious diseases resulting in huge losses to crops, especially wheat. Fungicides have been used to control it, but they have drawbacks, including residues and toxicity to mammals, which encouraged [...] Read more.
Fusarium is considered one of the most important fungi that attack plants and cause serious diseases resulting in huge losses to crops, especially wheat. Fungicides have been used to control it, but they have drawbacks, including residues and toxicity to mammals, which encouraged researchers to find alternatives to these methods and materials. This study was conducted to find natural alternatives to the chemicals used as fungicides. The Dodonaea viscosa plant extract was evaluated as an extract (DVE) and nanoparticles (chitosan NPs loaded with DVE) to inhibit the growth of Fusarium spp. strains and production ability of Deoxynivalenol (DON) and Moniliformin (MON) mycotoxins. The wheat samples were taken from storage in eighteen different governorates in Iraq. Fusarium spp. strains were detected phenotypically, and seven strains were identified by using the polymerase chain reaction technique (PCR) as F. oxysporum, F. pseudograminearum and F. chlamydosporum. DVE effectively inhibited the growth of Fusarium spp. strains at three different concentrations (0.5, 1.0, and 1.5%) on PDA. The highest percentage was 68.94% for F. oxysporum strain 5, and the lowest percentage was 22.58% for F. pseudograminearum strain 6 at a concentration of 1.5%. However, applying chitosan NPs loaded with DVE at a concentration of 0.75% effectively increased the inhibition rate. The treatment of chitosan NPs loaded with DVE played a role in inhibiting the percentage of mycotoxins produced. The highest percentage of inhibition of the DON toxin was recorded as 73.75% in Fusarium pseudograminearum strain 2, and the highest percentage of inhibition of the production of the (MON) toxin was 73.62% in isolate Fusarium chlamydosporum strain 8. Overall, this study highlights for the first time the potential of Dodonaea viscosa nano-formulation to suppress both fungal growth and mycotoxin biosynthesis, providing a sustainable and safe strategy for protecting stored grains. Full article
(This article belongs to the Special Issue Advances in Detection and Removal of Mycotoxins in Food)
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Review

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22 pages, 2245 KB  
Review
Adsorption–Degradation Integrated Approaches to Mycotoxin Removal from Food Matrices: A Comprehensive Review
by Xiyu Yang, Mingjian Yao, Wenchao Liao and Xiaoyang Li
Toxins 2025, 17(11), 556; https://doi.org/10.3390/toxins17110556 - 12 Nov 2025
Cited by 4 | Viewed by 2342
Abstract
Mycotoxin contamination is a crucial issue in food safety. However, the removal of trace amounts of mycotoxins from complex food and feed matrices without significant loss of nutritional and flavor quality remains a significant challenge. The integrated adsorption–catalysis strategy involves immobilizing catalytic modules [...] Read more.
Mycotoxin contamination is a crucial issue in food safety. However, the removal of trace amounts of mycotoxins from complex food and feed matrices without significant loss of nutritional and flavor quality remains a significant challenge. The integrated adsorption–catalysis strategy involves immobilizing catalytic modules onto adsorption materials, enabling in situ degradation while enriching the mycotoxins. This approach can significantly reduce the dosage of detoxification agents and achieve efficient removal of trace mycotoxins in food. This review provides an overview of adsorbents with enrichment capabilities and their applications in the targeted removal of mycotoxins from food. The adsorption–degradation coupled systems are categorized into the following two main types: adsorption–photocatalysis coupled systems and adsorption–biocatalysis coupled systems. The review introduces recent advances in the design of bifunctional catalysts, focusing on their synergistic mechanisms and practical applications for detoxifying various mycotoxins in food matrices. Finally, the review discusses current industrial challenges and offers insights into future directions for this field. Full article
(This article belongs to the Special Issue Advances in Detection and Removal of Mycotoxins in Food)
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