You are currently viewing a new version of our website. To view the old version click .

Symmetry

Symmetry is an international, peer-reviewed, open access journal covering research on symmetry/asymmetry phenomena wherever they occur in all aspects of natural sciences.
Symmetry is published monthly online by MDPI.
Quartile Ranking JCR - Q2 (Multidisciplinary Sciences)

All Articles (16,123)

Polycystic Ovary Syndrome (PCOS) is a widespread hormonal disorder affecting women of reproductive age, often leading to infertility and associated complications. This study presents a comprehensive stochastic mathematical framework to analyze the dynamics of PCOS with a particular focus on infertility and treatment outcomes. Here, the transitions between compartments represent progression of women through clinical states of PCOS (risk, diagnosis, treatment, recovery) rather than infection or transmission, since PCOS is a non-communicable disorder. The model incorporates probabilistic elements to break the symmetric and predictable assumptions inherent in deterministic approaches. This allows it to reflect the randomness and asymmetry in hormonal regulation and ovulation cycles, enabling a more realistic representation of disease progression. By utilizing stochastic differential equations, the study evaluates the impact of treatment adherence on fertility restoration. We establish the conditions for disease extinction versus the existence of an ergodic stationary distribution, which represents a form of long-term statistical symmetry. The results emphasize the importance of early diagnosis and consistent treatment. Furthermore, the proposed approach provides a valuable tool for clinicians to predict patient-specific trajectories and optimize individualized treatment plans, accounting for the asymmetric nature of patient responses.

27 October 2025

(a) Stochastic dynamics of the considered model (2) and (b) deterministic dynamics of the considered model (2).

This paper studies a generalized class of linear operators acting on spaces of analytic functions, defined by , where and . This formulation encompasses several classical operators, including composition, weighted composition, differentiation–composition, and the Stević–Sharma operator. We focus on the action of Pnψ,φ from BMOA and analytic Besov spaces Bp into the Bloch space B, and provide necessary and sufficient conditions for boundedness and compactness. These results unify and extend many previously known characterizations and demonstrate the flexibility of the Pnψ,φ framework in the context of analytic operator theory.

27 October 2025

The flow of a two-dimensional incompressible hybrid nanofluid over a stretching cylinder containing microorganisms with parallel effect of inclined magnetohydrodynamic was examined in the current study in relation to chemical reactions, heat source effect, nonlinear heat radiation, and multiple convective boundaries. The main objective of this research is the optimization of heat transfer with inclined MHD and variation in different physical parameters. The governing partial differential equations are transformed into a set of ordinary differential equations by applying the appropriate similarity transformations. The Runge–Kutta method is recognized for using shooting as a technique. Surface plots, graphs, and tables have been used to illustrate how various parameters affect the local Nusselt number, mass transfer, and heat transmission. It is demonstrated that when the chemical reaction parameter rises, the concentration and motile concentration profiles drop. The least responsive is the rate of heat transfer to changes in the inclined magnetic field and most associated with changes in the Biot number and radiation parameter shown in contour plot. The streamline graph illustrates the way fluid flow is affected simultaneously by the magnetic parameter M and an angled magnetic field. Local Nusselt number and local skin friction are improved by the curvature parameter and mixed convection parameter. The contours highlight the intricate interactions between restricted magnetic field, significant radiation, and substantial convective condition factors by displaying the best heat transfer. The three-dimensional surface, scattered graph, pie chart, and residual plotting demonstrate the statistical analysis of the heat transfer. The results support their use in sophisticated energy, healthcare, and industrial systems and enhance our theoretical knowledge of hybrid nanofluid dynamics.

27 October 2025

Chronic kidney disease (CKD) impacts over 850 million people globally, representing a critical public health issue, yet existing risk assessment methodologies inadequately address the complexity of disease progression trajectories. Traditional machine learning approaches encounter critical limitations including inefficient hyperparameter selection and lack of clinical transparency, hindering their deployment in healthcare settings. This study introduces an innovative computational framework that integrates adaptive Multi-Armed Bandit (MAB) strategies with BorderlineSMOTE sampling techniques to improve CKD risk assessment. The proposed methodology leverages XGBoost within an ensemble learning paradigm enhanced by Upper Confidence Bound exploration strategy, coupled with a comprehensive interpretability system incorporating SHAP and LIME analytical tools to ensure model transparency. To address the challenge of algorithmic interpretability while maintaining clinical utility, a four-level risk categorization framework was developed, employing cross-validated stratification methods and balanced performance evaluation metrics, thereby ensuring fair predictive accuracy across diverse patient populations and minimizing bias toward dominant risk categories. Through rigorous empirical evaluation on clinical datasets, we performed extensive comparative analysis against sixteen established algorithms using paired statistical testing with Bonferroni correction. The MAB-optimized framework achieved superior predictive performance with accuracy of 91.8%, F1-score of 91.0%, and ROC-AUC of 97.8%, demonstrating superior performance within the evaluated cohort of reference algorithms (p-value < 0.001). Remarkably, our optimized framework delivered nearly ten-fold computational efficiency gains relative to conventional grid search methods while preserving robust classification performance. Feature importance analysis identified albumin-to-creatinine ratio, eGFR measurements, and CKD staging as dominant prognostic factors, demonstrating concordance with established clinical nephrology practice. This research addresses three core limitations in healthcare artificial intelligence: optimization computational cost, model interpretability, and consistent performance across heterogeneous clinical populations, offering a practical solution for improved CKD risk stratification in clinical practice.

27 October 2025

News & Conferences

Issues

Open for Submission

Editor's Choice

Reprints of Collections

Electron Diffraction and Structural Imaging
Reprint

Electron Diffraction and Structural Imaging

Editors: Partha Pratim Das, Arturo Ponce-Pedraza, Enrico Mugnaioli, Stavros Nicolopoulos

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Symmetry - ISSN 2073-8994Creative Common CC BY license