Recent Advances in Green Extraction and Separation Processes

A special issue of Separations (ISSN 2297-8739).

Deadline for manuscript submissions: closed (20 September 2023) | Viewed by 2141

Special Issue Editors


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Guest Editor
College of Chemical and Biological Engineering, Shandong University of Science and Technology, Qingdao 266590, China
Interests: bioresource utilization; biomass valorization; biorefinery; biocatalysis; deep eutectic solvents; extraction and separation techniques; molecular simulation; life cycle assessment; green chemistry; bioactive compounds

E-Mail Website
Guest Editor
College of Chemical and Biological Engineering, Shandong University of Science and Technology, Qingdao 266590, China
Interests: green chemistry; bioresource utilization; biomass valorization; biorefinery

Special Issue Information

Dear Colleagues,

Extraction and separation are indispensable procedures in chemistry- and chemical-engineering-related processes. Proper choosing of the solvent which matches the target compound is an essential prerequisite. However, most of the conventional techniques used nowadays exhibit poor selectivity and low efficiency. Moreover, they involve the use of volatile and often toxic organic solvents, which leads to environmental concerns.

Fortunately, many researchers have been dedicated to exploring novel and green solvents which are bio-based and renewable to substitute polluting fossil-based organic solvents. These alternative solvents, including but not limited to ionic liquids, deep eutectic solvents, supercritical fluids, and aqueous two-phase systems, are deemed to be more environmentally friendly. Based on the understanding of the physicochemical properties of the specific target product, researchers can fine-tune or design a matching solvent, optimize the operational parameters, and thus greatly improve process efficiency. Although these advanced protocols are more efficient, their sustainability and applicability at larger scales remain to be addressed.

This Special Issue aims to publish the most recent advances and qualified studies which focus on green methods in extraction and separation. Research involving process sustainability and applicability at an industrial scale is also welcome. Moreover, the recycling and reuse of solvent, the life cycle assessment of the process, as well as green process exploration by means of computational simulation are also of interest in this issue.

Dr. Zhifang Cui
Dr. Guijiang Li
Guest Editors

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Keywords

  • deep eutectic solvents
  • ionic liquids
  • extraction
  • separation
  • solvent recyclability
  • sustainability
  • purification
  • green solvents
  • bioacitive products
  • simulation
  • life cycle assessment

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Published Papers (1 paper)

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Research

11 pages, 839 KiB  
Article
An Ultra-Fast and Green LC-MS Method for Quantitative Analysis of Aesculin and Aesculetin in Cortex Fraxini
by Xiaodong Wang, Wenhao Wang, Qinggui Lei, Zhengming Qian and Wenbin Deng
Separations 2023, 10(9), 515; https://doi.org/10.3390/separations10090515 - 19 Sep 2023
Viewed by 1853
Abstract
This study aims to develop a fast and eco-friendly liquid chromatography–mass spectrometry (LC-MS) method for the determination of aesculin and aesculetin in Cortex Fraxini. Ultrapure water was used as the solvent during the microwave-assisted extraction process to prepare the Cortex Fraxini sample. This [...] Read more.
This study aims to develop a fast and eco-friendly liquid chromatography–mass spectrometry (LC-MS) method for the determination of aesculin and aesculetin in Cortex Fraxini. Ultrapure water was used as the solvent during the microwave-assisted extraction process to prepare the Cortex Fraxini sample. This extraction method reduces the cost of the harmful solvent (only ultrapure water was used) and microwave extraction time (1 min). The LC separation was conducted using an Agilent InfinityLab Poroshell 120 EC-C18 column (2.1 mm × 30 mm, 2.7 µm) with a mobile phase consisting of 0.1% formic acid and acetonitrile (90:10, v/v) at a flow rate of 0.6 mL/min. Isocratic elution was employed, and the analytes were detected by MS. Through careful optimization and selection of LC-MS conditions, the analysis time was reduced to 1 min, demonstrating the method’s efficiency. The developed method was validated and exhibited excellent specificity, linearity, limit, precision, accuracy, and stability in quantifying aesculin and aesculetin in the Cortex Fraxini samples. The analysis result revealed the presence of aesculin (ranging from 3.55 to 18.8 mg/g) and aesculetin (ranging from 1.01 to 16.2 mg/g) in all ten batches of Cortex Fraxini samples. Compared to the reported LC methods, this approach substantially reduces the total analysis time and requires a minuscule volume of organic solvents. An “Analytical Eco-Scale” assessment was used to evaluate the different assay methods of Cortex Fraxini. The current LC-MS method scored an impressive 90; it was better than the other four reports’ LC methods. Thus, the developed LC-MS method is rapid and green, which is helpful for the quality evaluation of Cortex Fraxini. Full article
(This article belongs to the Special Issue Recent Advances in Green Extraction and Separation Processes)
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