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Wearable and Implantable Electrochemical Sensors

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Chemical Sensors".

Deadline for manuscript submissions: 20 September 2024 | Viewed by 2844

Special Issue Editors


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Guest Editor
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Interests: wearable and implantable electrochemical sensors and biosensors

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Guest Editor
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Interests: flexible and implantable medical sensing devices

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Guest Editor
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Interests: flexible electronics and wearable device
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Zhang Dayu School of Chemistry, Dalian University of Technology, Dalian 116024, China
Interests: wearable electrochemical sensors and flexible energy devices

Special Issue Information

Dear Colleagues,

We are pleased to announce the upcoming Special Issue on "Wearable and Implantable Electrochemical Sensors". The Special Issue aims to provide a platform for researchers and industry experts to share their latest research findings and technological advancements in the field of wearable and implantable electrochemical sensors. Wearable and implantable electrochemical sensors are highly specialized sensors that are designed to detect specific chemical analytes from body fluids (such as blood, interstitial fluid, sweat, etc.). These sensors based on electrochemical principles can provide real-time information about an individual's health status or disease progression. Furthermore, these sensors are wearable or implantable, making them highly portable and convenient for continuous monitoring over an extended period of time. The topics covered will include, but are not limited to, sensor design, fabrication, integration, signal processing, data analytics, and applications in various fields (such as biomedical, environmental monitoring, food safety, and personal wellbeing). Along with original research articles, we also welcome review papers and perspectives that offer insight into the challenges and opportunities in this exciting and rapidly evolving field of research. We invite researchers, engineers, and practitioners to submit their manuscripts for consideration in this Special Issue.

Dr. Zhanhong Li
Prof. Dr. Zhigang Zhu
Dr. Zifeng Wang
Prof. Dr. Nan Zhu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sensors
  • biosensors
  • wearable
  • implantable sensors
  • electrochemistry
  • flexible electronics
  • wireless communication
  • biocompatibility
  • real-time monitoring
  • self-powered sensors

Published Papers (4 papers)

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Research

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15 pages, 2954 KiB  
Article
Integration of Hollow Microneedle Arrays with Jellyfish-Shaped Electrochemical Sensor for the Detection of Biomarkers in Interstitial Fluid
by Fangfang Luo, Zhanhong Li, Yiping Shi, Wen Sun, Yuwei Wang, Jianchao Sun, Zheyuan Fan, Yanyi Chang, Zifeng Wang, Yutong Han, Zhigang Zhu and Jean-Louis Marty
Sensors 2024, 24(12), 3729; https://doi.org/10.3390/s24123729 - 8 Jun 2024
Viewed by 212
Abstract
This study integrates hollow microneedle arrays (HMNA) with a novel jellyfish-shaped electrochemical sensor for the detection of key biomarkers, including uric acid (UA), glucose, and pH, in artificial interstitial fluid. The jellyfish-shaped sensor displayed linear responses in detecting UA and glucose via differential [...] Read more.
This study integrates hollow microneedle arrays (HMNA) with a novel jellyfish-shaped electrochemical sensor for the detection of key biomarkers, including uric acid (UA), glucose, and pH, in artificial interstitial fluid. The jellyfish-shaped sensor displayed linear responses in detecting UA and glucose via differential pulse voltammetry (DPV) and chronoamperometry, respectively. Notably, the open circuit potential (OCP) of the system showed a linear variation with pH changes, validating its pH-sensing capability. The sensor system demonstrates exceptional electrochemical responsiveness within the physiological concentration ranges of these biomarkers in simulated epidermis sensing applications. The detection linear ranges of UA, glucose, and pH were 0~0.8 mM, 0~7 mM, and 4.0~8.0, respectively. These findings highlight the potential of the HMNA-integrated jellyfish-shaped sensors in real-world epidermal applications for comprehensive disease diagnosis and health monitoring. Full article
(This article belongs to the Special Issue Wearable and Implantable Electrochemical Sensors)

Review

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12 pages, 1926 KiB  
Review
Biocompatible Electrical and Optical Interfaces for Implantable Sensors and Devices
by Yuxin Wan, Caiyi Wang, Bingao Zhang, Yixuan Liu, Hailong Yang, Fengyu Liu, Jingjing Xu and Shengyong Xu
Sensors 2024, 24(12), 3799; https://doi.org/10.3390/s24123799 - 12 Jun 2024
Viewed by 227
Abstract
Implantable bioelectronics hold tremendous potential in the field of healthcare, yet the performance of these systems heavily relies on the interfaces between artificial machines and living tissues. In this paper, we discuss the recent developments of tethered interfaces, as well as those of [...] Read more.
Implantable bioelectronics hold tremendous potential in the field of healthcare, yet the performance of these systems heavily relies on the interfaces between artificial machines and living tissues. In this paper, we discuss the recent developments of tethered interfaces, as well as those of non-tethered interfaces. Among them, systems that study neural activity receive significant attention due to their innovative developments and high relevance in contemporary research, but other functional types of interface systems are also explored to provide a comprehensive overview of the field. We also analyze the key considerations, including perforation site selection, fixing strategies, long-term retention, and wireless communication, highlighting the challenges and opportunities with stable, effective, and biocompatible interfaces. Furthermore, we propose a primitive model of biocompatible electrical and optical interfaces for implantable systems, which simultaneously possesses biocompatibility, stability, and convenience. Finally, we point out the future directions of interfacing strategies. Full article
(This article belongs to the Special Issue Wearable and Implantable Electrochemical Sensors)
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32 pages, 8647 KiB  
Review
Advancements in Polymer-Assisted Layer-by-Layer Fabrication of Wearable Sensors for Health Monitoring
by Meiqing Jin, Peizheng Shi, Zhuang Sun, Ningbin Zhao, Mingjiao Shi, Mengfan Wu, Chen Ye, Cheng-Te Lin and Li Fu
Sensors 2024, 24(9), 2903; https://doi.org/10.3390/s24092903 - 1 May 2024
Viewed by 795
Abstract
Recent advancements in polymer-assisted layer-by-layer (LbL) fabrication have revolutionized the development of wearable sensors for health monitoring. LbL self-assembly has emerged as a powerful and versatile technique for creating conformal, flexible, and multi-functional films on various substrates, making it particularly suitable for fabricating [...] Read more.
Recent advancements in polymer-assisted layer-by-layer (LbL) fabrication have revolutionized the development of wearable sensors for health monitoring. LbL self-assembly has emerged as a powerful and versatile technique for creating conformal, flexible, and multi-functional films on various substrates, making it particularly suitable for fabricating wearable sensors. The incorporation of polymers, both natural and synthetic, has played a crucial role in enhancing the performance, stability, and biocompatibility of these sensors. This review provides a comprehensive overview of the principles of LbL self-assembly, the role of polymers in sensor fabrication, and the various types of LbL-fabricated wearable sensors for physical, chemical, and biological sensing. The applications of these sensors in continuous health monitoring, disease diagnosis, and management are discussed in detail, highlighting their potential to revolutionize personalized healthcare. Despite significant progress, challenges related to long-term stability, biocompatibility, data acquisition, and large-scale manufacturing are still to be addressed, providing insights into future research directions. With continued advancements in polymer-assisted LbL fabrication and related fields, wearable sensors are poised to improve the quality of life for individuals worldwide. Full article
(This article belongs to the Special Issue Wearable and Implantable Electrochemical Sensors)
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23 pages, 4329 KiB  
Review
Recent Progress in Wearable Near-Sensor and In-Sensor Intelligent Perception Systems
by Jialin Liu, Yitao Wang, Yiwei Liu, Yuanzhao Wu, Baoru Bian, Jie Shang and Runwei Li
Sensors 2024, 24(7), 2180; https://doi.org/10.3390/s24072180 - 28 Mar 2024
Viewed by 835
Abstract
As the Internet of Things (IoT) becomes more widespread, wearable smart systems will begin to be used in a variety of applications in people’s daily lives, not only requiring the devices to have excellent flexibility and biocompatibility, but also taking into account redundant [...] Read more.
As the Internet of Things (IoT) becomes more widespread, wearable smart systems will begin to be used in a variety of applications in people’s daily lives, not only requiring the devices to have excellent flexibility and biocompatibility, but also taking into account redundant data and communication delays due to the use of a large number of sensors. Fortunately, the emerging paradigms of near-sensor and in-sensor computing, together with the proposal of flexible neuromorphic devices, provides a viable solution for the application of intelligent low-power wearable devices. Therefore, wearable smart systems based on new computing paradigms are of great research value. This review discusses the research status of a flexible five-sense sensing system based on near-sensor and in-sensor architectures, considering material design, structural design and circuit design. Furthermore, we summarize challenging problems that need to be solved and provide an outlook on the potential applications of intelligent wearable devices. Full article
(This article belongs to the Special Issue Wearable and Implantable Electrochemical Sensors)
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