Medicinal Plants: Chemical Composition and Pharmacological Activity

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 499

Editors


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Guest Editor
Institute of Pharmacy, Faculty of Medicine, University of Tartu, 50411 Tartu, Estonia
Interests: pharmacy; pharmacognosy; phytochemistry; phytotherapy; ethnomedicine; ethnobotany; history of pharmacy
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Pharmacognosy and Nutriciology, National University of Pharmacy, 61002 Kharkiv, Ukraine
Interests: pharmacognosy; phytochemistry; phytotherapy; 3D-printing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Medicinal plants have long been integral to healthcare practices worldwide, providing important resources for disease prevention and treatment. Traditional knowledge regarding the use of plant materials and herbal preparations has developed over centuries; however, a substantial portion of this knowledge still lacks thorough validation using contemporary scientific methods. Despite the growing body of literature on medicinal plants, many plant-derived products remain insufficiently characterized in terms of their efficacy, safety, and underlying mechanisms of action.

In this regard, we invite researchers to submit original contributions focused on the phytochemical and pharmacological study of medicinal plants. This Special Issue of Plants seeks to highlight recent progress in identifying and characterizing bioactive constituents, determining their qualitative and quantitative profiles, assessing their biological and pharmacological properties, and advancing the development, standardization, and quality control of herbal-based products.

We particularly encourage submissions that address the isolation of plant-derived compounds, as well as studies that provide quantitative phytochemical analysis and evaluate their biological effects in vitro and in vivo. Research on the cultivation of medicinal plants, authentication of botanical materials, approaches to standardization, and the formulation of plant-based dosage forms is also within the scope of this Special Issue.

Manuscripts focusing solely on phytochemical screening without accompanying biological data, or exclusively pharmacological investigations lacking phytochemical characterization, will not be considered.

Prof. Dr. Ain Raal
Prof. Dr. Oleh Koshovyi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medicinal plants
  • plant raw materials
  • extracts
  • natural products
  • bioactive compounds
  • phytochemical characterization
  • compound isolation
  • pharmacological effects
  • dosage form development
  • standardization
  • quality control

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Published Papers (1 paper)

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Research

24 pages, 6572 KB  
Article
Anti-Complement, Anti-Oxidative, and Anti-Inflammatory Activities of the Ethanol Extract of Tamarix chinensis Lour.
by Muqing Wang, Min Cai, Xin Huang, Yu Liu, Congyu Wu, Yuan Gao and Yun Qi
Plants 2026, 15(14), 2199; https://doi.org/10.3390/plants15142199 - 18 Jul 2026
Viewed by 329
Abstract
Tamarix chinensis Lour. (T. chinensis) is a traditional herb with functions for releasing the exterior to promote the eruption of rashes, among other ailments. However, these function-related pharmacological effects, such as anti-complement, anti-oxidative, and anti-inflammatory, remain unclear. This study aims to [...] Read more.
Tamarix chinensis Lour. (T. chinensis) is a traditional herb with functions for releasing the exterior to promote the eruption of rashes, among other ailments. However, these function-related pharmacological effects, such as anti-complement, anti-oxidative, and anti-inflammatory, remain unclear. This study aims to reveal the aforementioned effects and the molecular mechanisms of the ethanol extract of T. chinensis (TCE). Our results demonstrated that TCE inhibited classical- and lectin-mediated complement activation, reduced intracellular ROS via NADPH oxidase inhibition, and directly scavenged DPPH radicals and superoxide anions. By using lipopolysaccharide (LPS)-stimulated macrophages, along with LPS-induced acute lung injury (ALI) and endotoxemia mice, the anti-inflammatory activity and the underlying molecular mechanisms of TCE were deeply investigated. In LPS-activated macrophages, it suppressed iNOS, CCL2, IL-6 and IL-1β transcriptionally and translationally. Mechanistically, TCE inhibited NF-κB signaling by blocking IκBα phosphorylation and p65 nuclear translocation, as well as suppresses AP-1 signaling by reducing ERK and JNK phosphorylation. In vivo, TCE lowered serum multiple pro-inflammatory cytokines of endotoxemic mice and alleviated lung injury of ALI mice. Collectively, our results demonstrated that TCE possesses anti-complement and anti-oxidative activities and exerts anti-inflammatory effects through inhibiting NF-κB and AP-1 signaling. These findings provide scientific evidence for supporting the traditional use of T. chinensis. Full article
(This article belongs to the Special Issue Medicinal Plants: Chemical Composition and Pharmacological Activity)
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