Bio-Control of Plant Pathogens and Pests

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Plant Protection and Biotic Interactions".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 892

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UF/IFAS Tropical Research and Education Center, Homestead, FL 33031, USA
Interests: molecular breeding; molecular diagnostics; virus–vector relationship; cell culture
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Special Issue Information

Dear Colleagues,

Crop productivity is significantly limited by plant diseases and insect pests, either by reducing the yield or increasing the production cost. While agricultural chemicals are widely used to address these challenges, their incessant use is associated with human and environmental hazards. These concerns are further amplified by the urgent need to ensure global food security for a rapidly growing population, while maintaining ecological balance. Consequently, the demand for sustainable disease and pest management strategies has increased markedly. Biological control measures are emerging as prominent alternatives to chemical-based control. Many of these strategies have demonstrated success in sustainably managing pests and diseases, offering the potential to reduce reliance on chemical inputs and mitigate associated issues such as environmental pollution and the evolution of resistant pest and pathogen populations.  

This Special Issue invites original research articles, reviews, and short communications encompassing all aspects of biological control, including the use of microbes and their metabolites, natural enemies and parasitoids, and integrated pest and disease management.

Dr. Sumit Jangra
Guest Editor

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Keywords

  • biological control of disease and pest
  • anti-microbial peptides
  • microbial volatile compounds
  • bioactive compounds
  • natural enemies
  • parasitoids
  • integrated pest and disease management

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Published Papers (2 papers)

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Research

21 pages, 867 KB  
Article
Management of Chilli Anthracnose Using Garcinia atroviridis Nanoemulsions Integrated with Trichoderma harzianum
by Yasmeen Siddiqui
Plants 2026, 15(8), 1214; https://doi.org/10.3390/plants15081214 - 15 Apr 2026
Abstract
Chilli is a major horticultural crop in tropical and subtropical regions that contributes substantially to the global culinary and economic sectors. However, anthracnose remains one of the most destructive diseases, causing severe losses in both field and stored fruits. Current management strategies offer [...] Read more.
Chilli is a major horticultural crop in tropical and subtropical regions that contributes substantially to the global culinary and economic sectors. However, anthracnose remains one of the most destructive diseases, causing severe losses in both field and stored fruits. Current management strategies offer limited long-term effectiveness, highlighting the need for sustainable alternatives. This study developed nanoemulsions (NEs) from Garcinia atroviridis fruit extract and evaluated their biocontrol potential against Colletotrichum capsici alone and in combination with Trichoderma harzianum. Two formulations, NE4 and NE7, exhibited good thermostability without phase separation at 25 and 54 °C, with droplet sizes of 135.1 and 124.1 nm, respectively, and were non-phytotoxic to chilli seedlings. In vitro, the nanoemulsions significantly suppressed C. capsici mycelial growth (62%) compared to the crude extract. Under rain shelter conditions, NE integrated with T. harzianum (T7 and T8) was highly effective in delaying disease onset and reducing disease severity, achieving 90.07% and 88.37% relative disease reduction, respectively. These treatments also produced the highest marketable yields, comparable to the synthetic fungicide Dithane M-45® (2 g L−1). In contrast, the untreated control group exhibited an 83% yield loss. The results indicate that nanoemulsions of G. atroviridis fruit extract, particularly when combined with T. harzianum, offer a promising and sustainable biological control option for managing pre-harvest chilli anthracnose. Their incorporation into integrated pest management programmes may reduce dependence on chemical fungicides and support safer chilli production systems. Full article
(This article belongs to the Special Issue Bio-Control of Plant Pathogens and Pests)
17 pages, 3748 KB  
Article
In Silico Screening of Plant-Derived Termiticidal Compounds Targeting Cytochrome P450 in Coptotermes spp. (Blattodea: Rhinotermitidae) for Sustainable Termite Management
by Deepak Kumar Mahanta, Tanmaya Kumar Bhoi and Sumit Jangra
Plants 2026, 15(4), 581; https://doi.org/10.3390/plants15040581 - 12 Feb 2026
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Abstract
Termites of the genus Coptotermes are among the most destructive structural pests worldwide, owing to their efficient lignocellulose degradation and metabolic adaptability mediated in part by cytochrome P450 enzymes. Although numerous botanical compounds have been reported to exhibit termiticidal activity, mechanistic in silico [...] Read more.
Termites of the genus Coptotermes are among the most destructive structural pests worldwide, owing to their efficient lignocellulose degradation and metabolic adaptability mediated in part by cytochrome P450 enzymes. Although numerous botanical compounds have been reported to exhibit termiticidal activity, mechanistic in silico studies targeting detoxification-related enzymes in Coptotermes, particularly cytochrome P450, remain limited. In this study, twenty-eight plant-derived bioactive compounds were evaluated using an integrated in silico framework comprising insecticide likeness screening, molecular docking, toxicity prediction, environmental fate assessment, and molecular dynamics simulation. Homology modeling enabled structural characterization of cytochrome P450 from C. formosanus, and subsequent screening identified 27 compounds with favorable physicochemical and ADMET properties. Molecular docking analysis highlighted Glyceollin, Cnicin, Biochanin A, Ferruginol, and ent-kaur-16-en-19-oic acid as strong binders, exhibiting stable interactions with conserved active-site residues. Toxicological and ecological assessments indicated generally low predicted risk to mammals, birds, and pollinators, while identifying potential sensitivity in aquatic organisms, emphasizing the need for controlled application. Molecular dynamics simulations further supported the stabilizing effect of Glyceollin on cytochrome P450 under simulated conditions. Overall, the study provides mechanistic insight into botanical inhibition of cytochrome P450 in Coptotermes and identifies promising candidate compounds for further experimental validation in sustainable termite management strategies. Full article
(This article belongs to the Special Issue Bio-Control of Plant Pathogens and Pests)
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