Novel Anticancer Strategies

Dear Colleagues,

The clinical efficacy of the available cancer therapies has been impaired by serious side effects and drug resistance. Cancer incidence and mortality continue to increase rapidly worldwide. Therefore, the development and discovery of novel therapeutic strategies are urgently needed in order to overcome the drawbacks associated with the strategies in use in the clinic, and to offer more effective therapeutic options. Novel cancer treatment strategies are being developed to selectively detect and eradicate malignant cells, with minimal damage to the healthy tissue, contrasted with conventional strategies.

In this Special Issue of Pharmaceutics, novel anticancer strategies with reduced toxicity and improved therapeutic indices, presented in original articles and comprehensive reviews highlighting the latest advances, are welcome. These strategies would suggest prospects for optimizing cancer therapies, hopefully with tremendous clinical value in the near future. Towards these aims, we encourage submissions that focus on the development and validation of novel anticancer approaches, which include, but are not limited to, ligand-/receptor-based targeting, controlled drug delivery, gene delivery, targeted anticancer prodrug and conjugate (photoactivatable caged prodrugs, ADEPT, ADAPT, ADCs), magnetic and ultrasound-mediated drug targeting, and cancer stem cell therapy that explores the targeting of signaling cascades and the tumor microenvironment.

Dr. Hassan Bousbaa
Guest Editor

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