Therapeutic Potential of Vitamin D in Depressive Disorder and Anxiety Disorders
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 15 November 2024 | Viewed by 1224
Special Issue Editor
Interests: animal models; neuroscience; behavioral pharmacology; neuropsychopharmacology; biological psychiatry; antidepressant agents
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Over the last two decades, the critical role of vitamin D in brain development and function has been highlighted. This neurosteroid has been implicated in proliferation, differentiation, maturation, and neuronal survival. In addition, its neuromodulatory properties on serotoninergic, glutamatergic, and dopaminergic neurotransmission have also been reported, and its neuroprotective effects related to anti-inflammatory and antioxidant functions have been the subject of extensive research. Particularly, vitamin D deficiency, a condition that affects a high percentage of global population, has been investigated as a risk factor for depression and anxiety. In this regard, several studies have examined the potential of vitamin D as an antidepressant and anxiolytic strategy. However, the mechanisms underlying the antidepressant and anxiolytic effects of vitamin D have not yet been fully elucidated. In this context, this Special Issue aims to highlight innovative studies investigating the possible mechanisms underlying the beneficial effects of vitamin D for depression and anxiety. Additionally, original research articles and review papers dealing with the efficacy of vitamin D supplementation for the treatment of depression and anxiety disorders are welcome.
Prof. Dr. Ana Lúcia Severo Rodrigues
Guest Editor
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Keywords
- antidepressant
- anxiety
- cholecalcipherol
- depression
- major depressive disorder
- vitamin D
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