From the Simple to the Complex in the Treatment of Chronic Inflammation: Supramolecular Devices Based on Cyclodextrins and Natural/Synthetic Polymer Derivatives

A special issue of Pharmaceuticals (ISSN 1424-8247).

Deadline for manuscript submissions: 12 May 2024 | Viewed by 261

Special Issue Editors


E-Mail Website
Guest Editor

E-Mail Website
Guest Editor
Departamento de Química del Medio Ambiente y Departamento de Química de Materiales, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile
Interests: host-guest interactions; macrocyclic receptors; self-assembled monolayers; supramolecular nanodevices; molecular recognition

Special Issue Information

Dear Colleagues,

Cyclodextrins (CDs) are oligosaccharides that are widely used as carrier systems for bioactive compounds due to their ability to form host–guest inclusion complexes. Hundreds of modified CDs are commercially available for use in research and industrial applications when the drugs have a limited bioavailability on the organism. However, only a limited number of modified cyclodextrins are currently used, mainly as pharmaceutical excipients. On the other hand, inflammation is a normal physiologic response that causes injured tissue to heal. An inflammatory process begins when chemical compounds are released from damaged tissue. In response, the white blood cells produce substances that cause the cells to divide and grow to rebuild tissue to help repair the injury. Once the wound heals, the inflammatory process will end.

Chronic inflammation can be caused by infections that do not go away, by abnormal immune reactions to normal tissues, or by conditions such as obesity. In this sense, the several medical studies about chronic inflammation, defined broadly as conditions that last 1 year or more and require ongoing medical attention and/or limit the activities of daily living, show that heart disease, arthritis, cancer, and diabetes are the leading causes of death and disability in the world.

Therefore, we invite researchers to contribute to this Special Issue with their experimental work, molecular modeling studies of active compounds and supramolecular structures, and pharmacological evaluations for the positive and potential treatment of chronic inflammations via the use of CD derivatives that will support the effective administration of the active principles of controlled methods.

Prof. Dr. Eduardo Sobarzo-Sánchez
Dr. Ana María Méndez-Torres
Guest Editors

Manuscript Submission Information

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Keywords

  • cyclodextrin
  • supramolecular devices
  • synthetic and natural polymers
  • chronic inflammation
  • nanoparticles and drug carriers

Published Papers

This special issue is now open for submission.
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