Advances in Dental Composite Materials

A special issue of Oral (ISSN 2673-6373).

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 4267

Special Issue Editor


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Guest Editor
Department of Dentistry, IRCCS San Raffaele Hospital and Dental School, Vita Salute University, 20132 Milan, Italy
Interests: restorative dentistry; dental biomaterials; CAD/CAM; composites
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Special Issue Information

Dear Colleagues,

Resin-based materials (RBCs) are widely used for dental restorative procedures. Their physical, chemical, mechanical, and biological properties are crucial for determining the quality and longevity of the restorations. Existing RBCs are characterized by improved mechanical strength, lower polymerization shrinkage and stress, and higher biocompatibility. Therefore, research has provided reliable materials that help clinicians to provide reliable restorative procedures. This Special Issue is devoted to the most recent research on these topics, addressing all aspects concerning the advances in the synthesis, modification, characterization, property, and applications of dental resin materials.

Prof. Dr. Gaetano Paolone
Guest Editor

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Keywords

  • dental resins
  • dental composites
  • photopolymerization
  • mechanical properties
  • resin-based composites
  • bulk-fill
  • resin cement
  • functional materials

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Published Papers (2 papers)

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Research

9 pages, 906 KiB  
Article
Effects of Ceramic Translucency and Thickness on Polymerization of a Photosensitive Resin Cement
by Abdullah Barazanchi, Jaafar Abduo, Yvonne Min-Joo Lee, Min-Suk Lee and Kai Chun Li
Oral 2023, 3(4), 490-498; https://doi.org/10.3390/oral3040040 - 30 Oct 2023
Viewed by 1189
Abstract
We investigated the effects of lithium disilicate ceramic thickness and translucency on the degree of polymerization of light-cured resin cement using the measure of hardness. Lithium disilicate specimens of three translucencies (low, medium and high) were prepared to four thicknesses (0.5, 1.0, 2.0 [...] Read more.
We investigated the effects of lithium disilicate ceramic thickness and translucency on the degree of polymerization of light-cured resin cement using the measure of hardness. Lithium disilicate specimens of three translucencies (low, medium and high) were prepared to four thicknesses (0.5, 1.0, 2.0 and 3.0 mm). A light-cured resin cement was cured through each of the ceramic specimens using a handheld curing light for 50 s. A 3D printed jig was used to achieve a uniform thickness of the resin cement. Directly cured resin cement was used as the control. Hardness was measured using nano-indentation to determine the degree of polymerization of the resin cement. Two-way ANOVA and Tukey post hoc tests were used to evaluate interaction between translucency and thickness. Hardness values from control specimens were assessed using the two-tailed t-test with the Bonferroni approach. The translucency of the specimens significantly influenced the hardness (p < 0.001), where a negative linear relationship between cement hardness and ceramic thickness was present for low translucency and high translucency. However, at a 0.5 mm thickness, all specimens showed similar hardness regardless of the translucency. The translucency of ceramics affected the hardness, and hence polymerization, of light-cure resin cement. However, the effect of increased thickness was a more significant factor. Full article
(This article belongs to the Special Issue Advances in Dental Composite Materials)
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19 pages, 2334 KiB  
Article
In Vitro Evaluation of Dental Resin Monomers, Triethylene Glycol Dimethacrylate (TEGDMA), and 2-Hydroxyethyl Methacrylate (HEMA) in Primary Human Melanocytes: A Pilot Study
by Shilpi Goenka
Oral 2023, 3(3), 353-371; https://doi.org/10.3390/oral3030029 - 3 Aug 2023
Cited by 6 | Viewed by 2395
Abstract
Triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA), two resin monomers often used in dental restorative materials, are leached due to insufficient polymerization and contact cells of the oral cavity. Despite reports on the cytotoxicity of these monomers on different oral cells, their [...] Read more.
Triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA), two resin monomers often used in dental restorative materials, are leached due to insufficient polymerization and contact cells of the oral cavity. Despite reports on the cytotoxicity of these monomers on different oral cells, their effects on oral melanocytes remain unknown. This first report provides novel data on the impact of TEGDMA and HEMA monomers on melanocyte viability and functions by utilizing primary human melanocytes from lightly pigmented (HEMn-LP) foreskin as a representative model of oral melanocytes. Results show that TEGDMA induced higher cytotoxicity than HEMA and significant morphological alterations (increased dendricity) in melanocytes at the lowest concentration of 0.25 mM onwards. HEMA achieved similar effects but only at an 8-fold higher concentration (2 mM), while lower concentrations did not induce any change in cellular melanin or morphology. HEMA suppressed intracellular tyrosinase activity at 1 and 2 mM, while TEGDMA had no effect, although none of the monomers altered tyrosinase activity directly in an acellular system. TEGDMA and HEMA did not alter cellular ROS production. TEGDMA suppressed LPS-induced IL-6 cytokine secretion in cells to a greater degree than HEMA, indicating its greater capacity to dampen the immune response. Our findings demonstrate that TEGDMA and HEMA at different concentrations induce cytotoxicity to melanocytes, stimulate their dendricity and impair immune responses, indicative of altered melanocyte homeostasis. Furthermore, it is worth considering alternative monomers in light of the cytotoxicity exhibited by TEGDMA at lower millimolar concentrations compared to HEMA as well as its significant impact on melanocyte differentiation and immune function. Full article
(This article belongs to the Special Issue Advances in Dental Composite Materials)
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