Special Issue "Dietary Modulation of the Immune Function: Direct and Microbiota Dependent Effects"

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Immunology".

Deadline for manuscript submissions: 15 December 2020.

Special Issue Editor

Dr. Francisco J. Pérez-Cano
Guest Editor
1. Section of Physiology, Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain
2. Nutrition and Food Safety Research Institute (INSA), 08921 Santa Coloma de Gramenet, Spain
Interests: immunonutrition; flavonoids; microbiota; oligosaccharides; probiotics; breast milk

Special Issue Information

Dear Colleagues,

Diet is critical in maintaining optimal immune function. Extensive research has demonstrated the immunomodulatory properties of particular nutrients. In this regard, some dietary components are able to modulate the immune response by interacting directly with the mucosal and systemic immune cells, activating receptors (e.g., vitamins) or changing membrane properties or modulating gene expression (e.g., fatty acids). However, some nutrients may influence immune function indirectly, after being metabolized by the microbiota, either  by generating new active components (e.g., polyphenol metabolites, short-chain fatty acids derived from fibre) or just by shaping microbiotal composition and functionality (e.g., probiotics and prebiotics), which in turn, will affect the immune response.

We invite authors to submit review articles and original research describing effects and mechanisms underlying the relationship between nutrition, microbiota and immunity. We are interested in articles describing these actions not only in humans but also in animal models, either in health or during pathological processes (e.g. infection, inflammation, autoimmunity), in which the nutrients or their metabolites may act by modulating the immune response.

Dr. Francisco J. Pérez-Cano
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • microbiota
  • probiotics
  • prebiotics
  • antioxidants
  • vitamins
  • polyphenols
  • flavonoids
  • PUFAs
  • fiber

Published Papers

This special issue is now open for submission.
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