The Impact of Dietary and Lifestyle Interventions on Liver Diseases
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".
Deadline for manuscript submissions: 25 November 2025 | Viewed by 3
Special Issue Editor
Special Issue Information
Dear Colleagues,
Liver diseases, including metabolic dysfunction-associated steatotic liver disease (MASLD)/metabolic dysfunction-associated steatohepatitis (MASH), liver fibrosis, cirrhosis, hepatocellular carcinoma (HCC), and other chronic liver diseases, constitute a significant and escalating global public health burden. Emerging research highlights dietary and lifestyle interventions as key strategies for mitigating disease onset, slowing progression, and potentially reversing liver pathology. Recent evidence also underscores microbiome modulation as an important mechanistic link between lifestyle factors and liver health. To overcome inherent challenges in conducting randomized controlled trials, advanced epidemiological methods such as target trial emulation have gained prominence, enabling robust causal inference from observational data. This Special Issue invites original research articles, systematic reviews, clinical trials, and methodological papers utilizing approaches such as target trial emulation, to comprehensively assess the impact of dietary interventions, lifestyle modifications, and microbiome-targeted strategies across the spectrum of chronic liver diseases. Our goal is to provide evidence-based insights that guide clinical practice, inform public health initiatives, and ultimately enhance patient outcomes worldwide.
Dr. Xiaotao Zhang
Guest Editor
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Keywords
- dietary interventions
- lifestyle interventions
- microbiome modulation
- target trial emulation
- MASLD/MASH
- liver fibrosis
- cirrhosis
- chronic liver diseases
- hepatocellular carcinoma
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