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Featured Reviews on Geriatric Nutrition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: 15 February 2026 | Viewed by 1495

Special Issue Editor

Special Issue Information

Dear Colleagues,

In the last century, the life expectancy at birth increased from roughly 45 years in the early 1900s to more than 80 years today.

Indeed, living longer is often related to different levels of frailty. Nevertheless, it is also true that many elderly people maintain good autonomy and live life with a good level of well-being. These subjects do not have serious illnesses or physical disabilities; they have good mental health, preserved cognitive functions, maintain a good level of physical activity levels, and in some cases, are engaged in social and productive activities. A healthy diet and lifestyle are important to reduce the risk of chronic diseases, many of which are age-related.

This Special Issue of Nutrients, entitled “Featured Reviews on Geriatric Nutrition”, has been developed to compile contemporary research studies on this important topic. We invite you and your collaborators to consider the submission of your original research, protocol development, methodological studies, narrative or systematic reviews, and meta-analyses. We welcome all types of study designs in various populations, including large observational epidemiological studies, systematic reviews and meta-analyses, clinical and field trials, and qualitative investigations.

Dr. Cristiano Capurso
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Mediterranean diet
  • nutrients
  • aging
  • frailty
  • determinants of health
  • cognitive decline
  • determinants of frailty and health in organs and systems

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Published Papers (1 paper)

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Review

28 pages, 2285 KiB  
Review
The Impact of Flavonoids and Omega-3 in Mitigating Frailty Syndrome to Improve Treatment Outcomes in Peripheral Artery Disease (PAD) Patients
by Sanaz Jamshidi, Zahra Eskandari, Amirhossein Faghih Ojaroodi, Shayan Keramat and Agata Stanek
Nutrients 2025, 17(14), 2303; https://doi.org/10.3390/nu17142303 - 12 Jul 2025
Viewed by 1098
Abstract
Peripheral artery disease (PAD) is a common vascular disorder in the elderly, often accompanied by frailty syndrome, which is associated with increased inflammation, oxidative stress, and functional decline. Nutritional strategies, particularly those involving bioactive compounds like flavonoids and omega-3 fatty acids, have been [...] Read more.
Peripheral artery disease (PAD) is a common vascular disorder in the elderly, often accompanied by frailty syndrome, which is associated with increased inflammation, oxidative stress, and functional decline. Nutritional strategies, particularly those involving bioactive compounds like flavonoids and omega-3 fatty acids, have been suggested as potential approaches to modulate these pathological processes. This narrative review summarizes current evidence regarding the anti-inflammatory and antioxidant effects of flavonoids and omega-3 fatty acids, and their possible roles in mitigating frailty syndrome in patients with PAD. We examine mechanistic pathways including NF-κB, AMPK, PI3K/Akt/mTOR, and Nrf2, which are implicated in chronic inflammation, endothelial dysfunction, and muscle wasting. Although studies in general and aging populations suggest beneficial effects of these compounds on vascular and muscle health, specific evidence in PAD patients remains limited. Flavonoids may reduce pro-inflammatory cytokine production and enhance antioxidant responses, while omega-3 fatty acids have shown potential in modulating inflammatory signaling and supporting vascular repair. Current data provide a basis for further investigation into the dietary modulation of frailty syndrome in PAD. Understanding the impact of these nutrients may offer insights into adjunctive strategies for improving patient outcomes. Full article
(This article belongs to the Special Issue Featured Reviews on Geriatric Nutrition)
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