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Nutrients
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Advances in Nutrition and Dietetics in Gastroenterology
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Advances in Nutrition and Dietetics in Gastroenterology

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 25 September 2025 | Viewed by 2716

Special Issue Editor

Prof. Dr. Marta Stelmach-Mardas

E-Mail Website
Guest Editor
Department of Obesity Treatment, Metabolic Disorders and Clinical Dietetics, Poznan University of Medical Sciences, 60-569 Poznan, Poland
Interests: diet-related diseases; gut microbiota; life quality assessment tools
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

All innovative studies across all areas of gastroenterology and hepatology are welcome! The management of gastrointestinal and hepatic diseases has been made possible through a better understanding of their underlying mechanisms. A proper diet and the use of pre- and probiotics may reduce the clinical symptoms of the diseases, abdominal discomfort, or influence the treatment outcome. The side effects related to oncological treatment directly influence the digestive system and liver function, leading to changes in body composition. Furthermore, the gut microbiota plays a significant role; the incidence of metabolic fatty liver disease (MASLD) is increasing due to the obesity epidemic; and the number of patients whose chronic metabolic liver disease leads to the development of hepatocellular carcinoma (HCC) is increasing.

Finally, the COVID-19 pandemic was a challenge for practitioners and patients in the medical world.

Prof. Dr. Marta Stelmach-Mardas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diet
  • management, metabolic fatty liver disease
  • cancer
  • gut microbiota
  • clinical symptoms
  • quality of life
  • body composition

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Published Papers (2 papers)

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Research

11 pages, 757 KiB  
Article
Is There Any Association Between Fat Body Mass and Bone Mineral Density in Patients with Crohn’s Disease and Ulcerative Colitis?
by Alicja Ewa Ratajczak-Pawłowska, Michał Michalak, Aleksandra Szymczak-Tomczak, Anna Maria Rychter, Agnieszka Zawada, Kinga Skoracka, Agnieszka Dobrowolska and Iwona Krela-Kaźmierczak
Nutrients 2025, 17(3), 466; https://doi.org/10.3390/nu17030466 - 28 Jan 2025
Viewed by 809
Abstract
Background: The study aimed to investigate the association between fat body mass and bone mineral density (BMD) of the lumbar spine (L1–L4), femoral neck, and total body. Methods: We studied 95 patients with Crohn’s disease (CD), 68 with ulcerative colitis (UC), [...] Read more.
Background: The study aimed to investigate the association between fat body mass and bone mineral density (BMD) of the lumbar spine (L1–L4), femoral neck, and total body. Methods: We studied 95 patients with Crohn’s disease (CD), 68 with ulcerative colitis (UC), and 40 healthy adults (control group—CG) aged 18–50 years old. The BMD of lumbar spine and femoral neck was assessed as well as body composition. Results: A lower fat mass percentage was observed in about 8% of CD, 13% of UC, and 3% of CG. An increased percentage of fat mass was common, and occurred above 50% of CD, 40% of UC, and about 60% of CG. Body fat mass and fat mass percentage were significantly lower among UC compared with the CG (p-value < 0.001) and CD (p-value < 0.01) in women. Body fat mass correlated positively with the BMD and T-score of L1–L4 and total body mass in men with UC. We found a positive correlation between the fat body mass and BMD and T-score of L1–L4, femoral neck, and total body in women with IBD. Among CG, positive correlations occurred between the fat body mass and BMD of L1–L4, BMD of total body, and T-score of total body, but only in men. CRP (C-reactive protein) correlated negatively with fat body mass only in men with CD. Conclusions: A higher fat mass percentage is common among IBD patients and healthy adults despite a normal body mass index. Body fat mass is a predictor of nutritional status and likely influences the course of the disease, as it correlated positively with BMD, T-score, and Z-score. The association between fat tissue and bone health appears to be stronger in women. Further studies are needed to investigate additional factors that may affect bone health in IBD. Full article
(This article belongs to the Special Issue Advances in Nutrition and Dietetics in Gastroenterology)
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22 pages, 4916 KiB  
Article
Very-Low-Absorbable Geraniol for the Treatment of Irritable Bowel Syndrome: A “Real-World” Open-Label Study on 1585 Patients
by Chiara Ricci, Ilaria Maria Saracino, Maria Chiara Valerii, Renato Spigarelli, Irene Bellocchio and Enzo Spisni
Nutrients 2025, 17(2), 328; https://doi.org/10.3390/nu17020328 - 17 Jan 2025
Viewed by 1571
Abstract
Objective: The objective of this study was to evaluate the efficacy of a very-low-absorbable geraniol formulation, administered as a food supplement, in patients with irritable bowel syndrome (IBS) in a real-world setting in Italy. Methods: This open-label study was conducted in Italy on [...] Read more.
Objective: The objective of this study was to evaluate the efficacy of a very-low-absorbable geraniol formulation, administered as a food supplement, in patients with irritable bowel syndrome (IBS) in a real-world setting in Italy. Methods: This open-label study was conducted in Italy on patients diagnosed with IBS and treated for 4 weeks with 240 mg/day of Palmarosa essential oil, absorbed on 960 mg of ginger root powder to obtain a very-low-absorbable geraniol formulation. Baseline characteristics, including demographic and symptoms were recorded using the IBS Severity Scoring System (IBS-SSS). After 28 ± 7 days, the patients were asked to complete the IBS-SSS questionnaire again. The primary objective was to confirm the effects of a very-low-absorbable geraniol formulation on self-reported symptoms of IBS and the quality of life of affected individuals. The secondary objective was to confirm the effect of the treatment on the different IBS subtypes. Results: A total of 1585 patients were included in the study, with a mean age of 44.8 years and 56.4% women. Following the 4-week supplementation period, significant decreases were observed in the patients’ IBS-SSS (−67.9%) and all the primary IBS symptoms, such as abdominal distention (−82.3%), unsatisfaction with bowel habits (−46.2%), and interference with quality of life (QoL) (−64.9%) (all p < 0.01). The patients’ stool type improved significantly. Treatment was effective in all IBS subtypes. Conclusions: Treatment with very-low-adsorbable geraniol food supplement was associated with improvements in symptoms and bowel habits in all IBS subtypes in a real-world setting in Italy. These findings support the use of geraniol as an effective option for patients with IBS regardless of the disease subtype. Full article
(This article belongs to the Special Issue Advances in Nutrition and Dietetics in Gastroenterology)
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