The Role of Phytochemicals in Metabolism and Immunity

Dear Colleagues,

The immune system modulates the functioning of cellular metabolism in different organs, including the liver, adipose tissue, pancreas, or brain. There is numerous evidence on the close relationship that exists between different metabolic alterations and an inadequate immune response, in which an altered microbiome composition may play a key role. Consequently, the restoration of immune function, directly or through the restoration of gut microbiome composition, will have a positive impact on the management of these metabolic diseases. The intake of edible phytochemicals is among one of the possible therapeutic strategies with beneficial effects in these situations, since they contain active ingredients of a different nature, such as polyphenols, which have been demonstrated to exert different biological properties, including their immunomodulatory capacity and/or prebiotic properties, being able to restore the cellular functioning affected in these metabolic diseases.

We are pleased to invite you to collaborate on this Special Issue, entitled ‘The Role of Phytochemicals in Metabolism and Immunity’, which aims to collect articles focused on the evaluation of the impact of well-characterized dietary phytochemicals in different metabolic conditions, following both preclinical and clinical studies. These studies could describe novel effects for these phytochemicals or their benefits in comparison with other standardized therapies, which could make then attractive as novel therapeutic strategies in the management of these metabolic diseases.

In this Special Issue, original research articles as well as reviews are welcome. Research areas may include, but are not limited to, the following:

• Glucose metabolism disorders;
• Metabolic syndrome;
• Lipid metabolism disorders;
• Disorders of calcium metabolism;
• Malabsorption syndromes;
• Iron metabolism disorders;
• Mitochondrial diseases;
• Metabolic brain diseases.

I look forward to receiving your contributions.

Prof. Dr. Julio Galvez
Guest Editor

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• polyphenols
• gut microbiota
• immune response
• metabolic disease
• phytochemicals