Research Innovations in Skin and Wound Care

A special issue of Nursing Reports (ISSN 2039-4403).

Deadline for manuscript submissions: 30 June 2026 | Viewed by 7560

Special Issue Editors


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Guest Editor
School of Nursing, Queensland University of Technology, Kelvin Grove, QLD 4059, Australia
Interests: wound care; venous leg ulcers; non-healing; delayed healing; recurrence; risk assessment tools; validation; reliability

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Guest Editor
School of Nursing, Queensland University of Technology, Kelvin Grove, QLD 4059, Australia
Interests: chronic disease; self-management; exercise; behaviour change; implementation science; randomised controlled trials

Special Issue Information

Dear Colleagues,

Research innovations in skin and wound care have made significant strides in recent years, revolutionising the way healthcare professionals approach the management of skin integrity and wound healing.

Furthermore, the integration of digital health tools, such as telemedicine and mobile health applications, is transforming patient monitoring and education, allowing for personalised care strategies. As these innovations continue to emerge and interprofessional healthcare professionals are highlighted as being important, there is the potential to significantly improve patient outcomes, reduce healthcare costs, and enhance the overall quality of life for individuals affected by skin and wound conditions.

This Nursing Reports Special Issue on “Research Innovations in Skin and Wound Care” will provide a platform to highlight research projects focused on innovative solutions to the challenge of skin and wound care by healthcare professionals in hospital and community settings.

This timely dialogue is highly relevant. As the prevalence of chronic wounds continues to rise due to factors such as diabetes, ageing populations, and increased surgical procedures, the need for advanced therapeutic solutions is more critical than ever.

Dr. Christina Parker
Dr. Jane O'Brien
Guest Editors

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Keywords

  • wound care
  • skin care
  • digital wound care
  • skin integrity
  • wound management
  • wound care innovation

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Published Papers (3 papers)

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Research

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18 pages, 2229 KB  
Article
Effectiveness of the Training Given According to Self-Care Deficit Nursing Theory in the Prevention of Peristomal Skin Complications
by Ali Ay and Hülya Bulut
Nurs. Rep. 2026, 16(5), 155; https://doi.org/10.3390/nursrep16050155 - 5 May 2026
Abstract
Background/Objectives: Peristomal skin complications are common among individuals with a stoma and are associated with decreased quality of life, increased healthcare costs, social isolation, and various other challenges. However, these complications can often be prevented through appropriate care, patient education, counseling, and [...] Read more.
Background/Objectives: Peristomal skin complications are common among individuals with a stoma and are associated with decreased quality of life, increased healthcare costs, social isolation, and various other challenges. However, these complications can often be prevented through appropriate care, patient education, counseling, and follow-up. This quasi-experimental study aimed to evaluate the effectiveness of education based on Orem’s Self-Care Deficit Nursing Theory (SCDNT) in preventing peristomal skin complications. Methods: The study included 45 patients with newly formed stomas, allocated to an experimental group (n = 24) and a control group (n = 21) using a nonrandomized approach. Both groups received routine postoperative education, while the experimental group additionally received structured education, counseling, and follow-up based on SCDNT. Data were collected using the Patient Characteristics Form, Self-Care Agency Scale (SCAS), Stoma Quality of Life Scale (SQOL), Patient Outcomes Evaluation Form, and Patient Opinions Questionnaire. Results: Among the participants, 73.3% had undergone stoma surgery due to cancer, and 53.3% had an ileostomy. Peristomal skin complications were observed in 54.2% of patients in the experimental group and 95.2% in the control group (p < 0.05). The most frequently reported complications were irritant dermatitis (71.4%) and hyperplasia (22.7%). The mean recovery time was shorter in the experimental group (21 ± 12.95 days) compared to the control group (44.65 ± 23.56 days) (p < 0.05). Conclusions: SCDNT-based education, counseling, and follow-up may be associated with lower rates and shorter durations of peristomal skin complications and earlier patient engagement in self-care. However, these findings should be interpreted with caution due to the nonrandomized design, small sample size, and differences in follow-up intensity. Further randomized controlled studies are recommended to confirm these findings. Full article
(This article belongs to the Special Issue Research Innovations in Skin and Wound Care)
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22 pages, 1455 KB  
Article
Outcomes of a Risk-Stratified Protocol for Preventing Peristomal Skin Complications in Patients with an Ostomy: A Cohort Study
by Francesco Carlo Denti, Eliana Guerra, Francesca Caroppo, Pietro Abruzzese, Fabrizio Alessi, Filippo Barone, Pasqualina Bernardino, Massimiliano Bergamini, Maria Cristina Bernardo, Gloria Bosio, Paula Carp, Manuela Cecconello, Annalinda Cerchier, Francesca Croci, Rita Detti, Mina Milenova Dimitrova, Cristina Di Pasquale, Maria Rosaria D'Ippolito, Simona Ditta, Erica Ducci, Anna Belloni Fortina, Stefano Frascarelli, Marianna Galante, Rita Guarino, Nicola Leggio, Elisabetta Livio, Alessandra Marchetti, Francesca Marelli, Rita Mastropaolo, Viviana Melis, Nicola Palmiero, Arianna Panarelli, Anna Lea Pascali, Francesco Pizzarelli, Laura Precisi, Cinzia Rastello, Silvia Regaglia, Rossana Elvira Rinaldi, Nadia Rumbolo, Claudio Sansone, Angela Santelli, Giovanni Sarritzu, Stefano Sfondrini, Sara Stanzani, Mattia Stella, Margherita Walterova and Rosario Carusoadd Show full author list remove Hide full author list
Nurs. Rep. 2025, 15(5), 179; https://doi.org/10.3390/nursrep15050179 - 20 May 2025
Cited by 6 | Viewed by 4046
Abstract
Background/Objectives: Peristomal skin complications (PSCs) are common among patients with ostomies, significantly impacting quality of life and increasing healthcare utilization. This study aimed to evaluate the effects of the Dermamecum protocol, a risk-stratified educational intervention, on the prevention of PSCs, self-care improvements, health-related [...] Read more.
Background/Objectives: Peristomal skin complications (PSCs) are common among patients with ostomies, significantly impacting quality of life and increasing healthcare utilization. This study aimed to evaluate the effects of the Dermamecum protocol, a risk-stratified educational intervention, on the prevention of PSCs, self-care improvements, health-related quality of life (HRQoL), and patient satisfaction over a 90-day follow-up period. Methods: This prospective cohort study included 305 patients stratified into three risk-based groups (green, yellow, and red paths) according to the Dermamecum protocol. Primary outcomes included PSC rates at 30, 60, and 90 days. Secondary outcomes included self-care scores, HRQoL, and patient satisfaction. Comparative analyses and trend assessments were performed across groups and time points. Temporal trends in PSCs were analyzed using Poisson regression. Results: Early PSC rates were 8.5% at 30 days, with late complications at 7.9% and 6.2% at 60 and 90 days, respectively. No significant differences in PSC rates were observed between paths. Self-care scores improved over time, with stability across groups and domains. HRQoL remained stable, with minor fluctuations in physical and mental components. Patient satisfaction was high across all paths. Poisson regression identified significant temporal trends in PSC rates, with higher risks at 30, 60, and 90 days compared to baseline. Age, BMI, and path assignment (lower risk for the green path) were significant predictors of PSCs. Conclusions: The Dermamecum protocol effectively maintained low PSC rates, supported self-care, and sustained HRQoL and patient satisfaction. These findings highlight the value of risk-stratified, patient-centered interventions in ostomy care. Further studies are needed to validate these results and explore long-term outcomes. Full article
(This article belongs to the Special Issue Research Innovations in Skin and Wound Care)
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Review

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14 pages, 554 KB  
Review
Topical Ozone as an Adjuvant Therapy in Wound Management: An Integrative Review
by Cristina Barroso Pinto, Adelino Pinto, Manuela Barroso, Telma Coelho and Sandra Costa
Nurs. Rep. 2025, 15(12), 414; https://doi.org/10.3390/nursrep15120414 - 25 Nov 2025
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Abstract
Background/Objectives: Wound management remains a clinical challenge, particularly in chronic and refractory conditions. Ozone, due to its antimicrobial, anti-inflammatory, and tissue-regenerative properties, has emerged as promising adjuvant therapy. This integrative re-view aimed to critically analyze the therapeutic effects, routes of administration, benefits, and [...] Read more.
Background/Objectives: Wound management remains a clinical challenge, particularly in chronic and refractory conditions. Ozone, due to its antimicrobial, anti-inflammatory, and tissue-regenerative properties, has emerged as promising adjuvant therapy. This integrative re-view aimed to critically analyze the therapeutic effects, routes of administration, benefits, and limitations of ozone in wound treatment. Methods: The review followed the Joanna Briggs In-stitute methodology and the PRISMA 2020 guidelines. Studies were identified through compre-hensive search in the SCOPUS, CINAHL Ultimate, MEDLINE Ultimate, and MedicLatina data-bases, with no time restrictions. Inclusion criteria encompassed primary studies involving adults (≥18 years) with wounds treated with ozone. The methodological quality of the selected studies was assessed using the tools recommended by JBI. Results: Nine reports published between 2019 and 2025 met the inclusion criteria. The findings consistently demonstrated clinical benefits of ozone therapy, including accelerated wound healing, pain reduction, and infection control. The forms of application included ozonated water, ozonated olive oil, and gaseous ozone. However, heterogeneity was observed in ozone concentration, frequency, and treatment duration. The methodological quality of the included studies ranged from moderate to high. Conclusions: The available evidence indicates that ozone may represent promising adjuvant treatment for certain types of wounds; however, the quality and independence of the existing studies are limited, and the lack of standardized protocols as well as methodological variability restrict the generalizability of the findings. Therefore, more robust clinical trials are needed to strengthen the evidence base and support its clinical implementation. Full article
(This article belongs to the Special Issue Research Innovations in Skin and Wound Care)
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