Nanobiomaterials in Therapy and Medical Diagnosis

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: 30 October 2026 | Viewed by 1327

Editors


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Guest Editor
Department of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Krakow, 30-059 Krakow, Poland
Interests: polymeric biomaterials; composites; materials characterization; biomedical engineering; scaffolds for tissue engineering
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Guest Editor
Institute of Materials Technology, Universitat Politècnica de València, 46022 Valencia, Spain
Interests: graphene composites; supercapacitors; optoelectronics; electrochemical sensing; photocatalysis; surface modification; corrosion
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Theranostics, combining therapy and diagnostics, is currently a dynamically developing field of science based on nanobiomaterials in the form of nanostructured materials such as nanocomposites, nanoparticles, nanolayers, or other nanometric forms. Polymers, ceramics, metals (including magnetic nanoparticles), nanometric forms of carbon, and biological structures are used here. New-generation nanobiomaterials in this field combine multifunctional solutions with specific composition and structure reacting to an external stimulus (smart materials). The development of such materials requires an interdisciplinary approach combining materials engineering, biomedical engineering, biotechnology, and medicine.

This Special Issue aims at enabling scientists to share their current scientific achievements in the development of nanobiomaterials intended for use in the broadly understood field of theranostics, including drug and biological molecule delivery (genes and aptamers), targeted therapy, cancer therapy, medical imaging and diagnostics, scaffolds for tissue engineering delivering biologically active agents, and in the treatment of bacterial infections.

Dr. Anna Morawska-Chochol
Dr. Alina Iuliana Pruna
Guest Editors

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Keywords

  • drug and gene delivery
  • tissue engineering
  • nanocomposites
  • polymeric, ceramic, and metallic nanoparticles
  • nanometric form of carbon
  • therapy
  • imaging
  • antimicrobial and antifouling
  • theranostic

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Published Papers (1 paper)

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Review

43 pages, 13727 KB  
Review
Adaptive Quantum Dot Biointerfaces for Precision Wound Repair
by Hossein Omidian, Kwadwo Amanor Mfoafo and Luigi X. Cubeddu
Nanomaterials 2026, 16(12), 774; https://doi.org/10.3390/nano16120774 - 19 Jun 2026
Viewed by 919
Abstract
Impaired wound healing arises from interacting biological and material challenges, including persistent infection, biofilm formation, oxidative stress, unresolved inflammation, impaired angiogenesis, defective epithelialization, hemorrhage, and insufficient real-time assessment of wound status. Quantum dot (QD) and nanodot nanosystems have emerged as a versatile class [...] Read more.
Impaired wound healing arises from interacting biological and material challenges, including persistent infection, biofilm formation, oxidative stress, unresolved inflammation, impaired angiogenesis, defective epithelialization, hemorrhage, and insufficient real-time assessment of wound status. Quantum dot (QD) and nanodot nanosystems have emerged as a versatile class of bioactive wound interfaces capable of addressing these barriers through functions that extend beyond passive coverage. This review synthesizes the design rationale, material composition, validation strategies, functional outcomes, mechanistic interpretation, and translational relevance of QD-enabled platforms for precision wound repair. Across the reviewed literature, carbon dots, graphene QDs, black phosphorus QDs, metal and metal oxide QDs, transition-metal nanodots, and hybrid nanocomposites were incorporated into hydrogels, films, sponges, nanofibers, microneedles, scaffolds, membranes, sprays, and injectable matrices. Their major precision-enabling attributes include localized antimicrobial and antibiofilm activity, redox-adaptive behavior, photothermal and photodynamic activation, inflammatory and macrophage modulation, hemostasis, controlled therapeutic delivery, angiogenic and epithelial support, and fluorescence-based monitoring. The strongest conceptual advance is the transition from static wound dressings toward adaptive biointerfaces that can sense, respond to, or compensate for local wound state abnormalities. Nevertheless, the field remains largely preclinical, with important gaps in long-term safety, standardized characterization, clinically predictive models, manufacturing reproducibility, regulatory alignment, and human validation. Future progress will depend on rationally simplified multifunctional platforms, rigorous comparative testing, wound state-specific evaluation frameworks, and translation-oriented safety and usability studies. QD nanosystems therefore represent a promising foundation for precision wound repair, provided that their multifunctionality is matched by equally rigorous evidence of safety, reproducibility, and clinical relevance. Full article
(This article belongs to the Special Issue Nanobiomaterials in Therapy and Medical Diagnosis)
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