E-Mail Alert

Add your e-mail address to receive forthcoming issues of this journal:

Journal Browser

Journal Browser

Special Issue "Nucleosides, Nucleotides, and Their Derivatives, Analogs, and Oligomers"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 30 June 2020

Special Issue Editor

Guest Editor
Prof. Wojciech T. Markiewicz

Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznań, Poland
Website | E-Mail
Phone: +48 601 793 527
Interests: nucleosides; nucleotides; oligonucleotide synthesis; chemical RNA synthesis; protecting groups; silyl protecting groups; combinatorial chemistry; epigenetic drugs; induced pluripotent stem cells (i-PSC); anticancer compounds

Special Issue Information

Dear Colleagues,

Nucleosides and nucleotides have drawn the attention of scientists for almost two centuries. The inosine nucleotide might be seen as a spectacular example of "scientific longevity" of this class of compounds, sparking the interest of researchers since its first isolation by Justus Liebig in 1847 (doi:10.1002/jlac.18470620302), with one of the latest reports (26 December 2018; doi:10.1073/pnas.1814367115) suggesting its primordial function in the development of the “RNA world”.

Nucleosides and nucleotides as components of native nucleic acids are the building blocks of chemically derived nucleic acids fragments, and form the basis of molecular tools of contemporary biology, xenobiology, and medicine, just to mention but a few, such as cloning, DNA/RNA sequencing, and diagnostics. Their use as antiviral and anticancer drugs, and nucleoside antibiotics, as well as their applications in nanotechnology, and their use in new materials development touches on some other areas of their important and perspective applications. The tremendous progress in understanding the live processes that have been achieved so far would not take place without studies on this group of molecules. This Special Issue aims to provide a forum for the dissemination of the latest information on the synthesis, isolation, properties, and applications of new nucleosides and nucleotides, as well as their analogs, oligomers, conjugates, materials, and drugs based-on, and so on.

Prof. Wojciech T. Markiewicz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • nucleoside
  • nucleotide
  • nucleoside analog
  • nucleotide analog
  • synthesis
  • structure
  • biological activity
  • oligomers
  • protecting group
  • xenobiology
  • anticancer drug
  • antiviral nucleoside derivative
  • anticancer nucleoside analog
  • nucleoside antibiotics
  • epigenetic nucleoderived drugs
  • nanomaterial

Published Papers

This special issue is now open for submission.
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top