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Special Issue "Exploitation of Multifunctional Nanomaterials for Biological Applications"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Nanochemistry".

Deadline for manuscript submissions: 31 October 2019

Special Issue Editors

Guest Editor
Prof. Marco Rossi

Department of Basic and Applied Sciences, Sapienza University of Rome, via A. Scarpa 16, 00161 Rome, Italy
Website | E-Mail
Interests: electron microscopy; electron diffraction; nanocharacterizations; nanotechnology; carbon nanomaterials
Guest Editor
Dr. Daniele Passeri

Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Via A. Scarpa 14, 00161 Rome, Italy
Website | E-Mail
Phone: +39 06 49766591
Interests: nanocharacterizations; scanning probe microscopy; nanotechnology; nanoscience; atomic force microscopy
Guest Editor
Dr. Francesca A. Scaramuzzo

Department of Basic and Applied Sciences for Engineering (SBAI), Sapienza University of Rome, Via del Castro Laurenziano 7, 00161 Rome, Italy
Website | E-Mail
Interests: materials science; nanomaterials; organic-inorganic hybrids; coordination compounds chemistry; molecular recognition

Special Issue Information

Dear Colleagues,

The development and spreading of nanomaterials are leading to an authentic revolution in science and technology. Behaving differently from bulk materials, nanomaterials can be tuned in shape, composition, and dimensions, giving rise to a variety of physico-chemical features and properties. The biological and biomedical fields are taking great advantage of the use of nanomaterials, since these can act as probes, carriers, or scaffolds. Moreover, the possibility to combine more chemical features and moieties in the same nanosystem (e.g., nanocomposites, core–shell nanostructures, organic–inorganic hybrids) has opened new perspectives in the design of smart nanoplatforms which can be potentially used to obtain multifunctional devices.

The Special Issue “Exploitation of Multifunctional Nanomaterials for Biological Applications” will cover the synthesis, characterization, and cutting-edge biological applications of multifunctional nanomaterials, including new and green production strategies, multiplatforms for sensing and theragnostics, smart structural and functional nanosystems. Theory, design optimization, and mechanistic studies of nanomaterials–biomolecules interactions will be covered as well.

We are pleased to invite you to submit a manuscript to this Special Issue. Full research papers, short communications, and review papers covering the aforementioned topics are welcome.

Prof. Marco Rossi
Dr. Daniele Passeri
Dr. Francesca Scaramuzzo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Biomaterials
  • Nanomaterials for theragnostics
  • Nanoplatforms for biomolecular sensing
  • Biocompatible nanomaterials
  • Biomedical nanoprobes
  • Antibacterial
  • Drug delivery
  • Green synthesis of nanocomposites
  • Nanomaterials for the environment
  • Toxicity of nanomaterials
  • Characterization at the nanoscale
  • Theory and modelling of nanomaterials–biomolecules interactions

Published Papers (1 paper)

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Open AccessArticle
The Stimulatory Effects of Nanochitin Whisker on Carbon and Nitrogen Metabolism and on the Enhancement of Grain Yield and Crude Protein of Winter Wheat
Molecules 2019, 24(9), 1752; https://doi.org/10.3390/molecules24091752
Received: 31 March 2019 / Revised: 26 April 2019 / Accepted: 3 May 2019 / Published: 6 May 2019
PDF Full-text (1181 KB) | HTML Full-text | XML Full-text
Nanochitin whisker (NC) with a cationic nature could enhance plant photosynthesis, grain yield, and quality of wheat, but have not been systematically studied. This study was designed to investigate the stimulatory effects of NC on dry matter (DM) and nitrogen (N) accumulation and [...] Read more.
Nanochitin whisker (NC) with a cationic nature could enhance plant photosynthesis, grain yield, and quality of wheat, but have not been systematically studied. This study was designed to investigate the stimulatory effects of NC on dry matter (DM) and nitrogen (N) accumulation and translocation, and on the metabolism of carbon (C) and N in later growth stages of winter wheat to reveal the enhancement mechanism of grain yield and crude protein concentration. Different parts of NC-treated plants from pot grown experiments were collected at the pre- and post-anthesis stages. The accumulation, translocation, and contributions of DM and N from pre-anthesis vegetation organs to grains, as well as key metabolic enzyme activities, including sucrose phosphate synthase (SPS) and phosphoenolpyruvate carboxylase (PEPC), were examined. The results showed that, at an application rate of 6 mg·kg−1 of NC in the soil, the accumulation of DM and N were significantly enhanced by 16.2% and 38.8% in pre-anthesis, and by 15.4% and 30.0% in post-anthesis, respectively. Translocation of N and DM in the post-anthesis periods were enhanced by 38.4% and 50.9%, respectively. NC could also stimulate enzyme activities, and increased 39.8% and 57.1% in flag leaves, and by 36.0% and 58.8% in spikes, respectively, at anthesis. SPS and PEPC increased by 28.2% and 45.1% in flag leaves, and by 42.2% and 56.5% in spikes, respectively, at 15 days after anthesis. The results indicated that the NC promoted N metabolism more than C metabolism, and resulted in the enhancement of grain yield by 27.56% and of crude protein concentration in grain by 13.26%, respectively. Full article

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