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Chemical Approaches in Food Quality and Safety

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Food Chemistry".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 546

Special Issue Editor


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Guest Editor
Department of Food Engineering, Faculty of Engineering and Natural Sciences, Hitit University, 19030 Corum, Turkey
Interests: food safety; chemical hazards; food contaminants; mycotoxins; pesticide residues; chemical risk assessment; exposure assessment; chromatographic techniques; method validation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Ensuring food quality and safety within today’s increasingly complex and interdependent global supply chains is a major scientific and regulatory challenge. The expanding chemical diversity of modern food systems, shaped by intensified production practices, environmental stressors, technological innovation, and the emergence of new contaminants, necessitates robust, highly sensitive, and forward-looking chemical strategies. In this evolving landscape, the chemical sciences are indispensable. They provide not only state-of-the-art analytical instrumentation but also the theoretical and methodological foundations necessary for the precise characterization, quantification, transformation analysis, and effective control of compounds governing food integrity, authenticity, and toxicological safety.

This Special Issue seeks to assemble high-quality contributions that advance analytical, bioanalytical, and chemometric methodologies for comprehensive food system evaluation. Particular emphasis will be placed on innovative sample preparation strategies, advanced chromatographic and mass spectrometric techniques, non-targeted and spectroscopic approaches, and data-driven chemometric tools that enhance analytical reliability and interpretability. Original research articles addressing chemical contaminants, including pesticide residues, mycotoxins, process contaminants, environmental pollutants, and migrants from food contact materials, as well as studies on authenticity, adulteration detection, and risk-oriented chemical profiling, are especially encouraged. Contributions presenting rigorous method development and validation, mechanistic investigations of chemical transformations during processing and storage, and integrative approaches linking analytical chemistry with exposure science and safety assessment are strongly welcomed. Review articles presenting the current state of knowledge on the above topic are also welcome.

Prof. Dr. Bulent Kabak
Guest Editor

Manuscript Submission Information

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Keywords

  • food safety
  • analytical chemistry
  • contaminants
  • mycotoxins
  • pesticides
  • heavy metals
  • process contaminants
  • environmental contaminants
  • food contact materials
  • emerging contaminants
  • adulteration
  • dietary exposure
  • risk assessment
  • chromatographic methods
  • mass spectrometry
  • chemometrics

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Published Papers (1 paper)

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Research

16 pages, 1596 KB  
Article
Co-Occurrence of 5-Hydroxymethylfurfural and Patulin in Reconstituted Pomegranate Juice: Analytical Determination and Risk Assessment
by Cagla Kayisoglu
Molecules 2026, 31(8), 1309; https://doi.org/10.3390/molecules31081309 - 17 Apr 2026
Viewed by 317
Abstract
5-Hydroxymethylfurfural (5-HMF) and the mycotoxin patulin (PAT) serve as crucial chemical markers for evaluating the quality and safety of fruit-derived beverages, particularly pomegranate juice. This study aimed to quantify the occurrence of 5-HMF and PAT in commercial reconstituted pomegranate juices and assess the [...] Read more.
5-Hydroxymethylfurfural (5-HMF) and the mycotoxin patulin (PAT) serve as crucial chemical markers for evaluating the quality and safety of fruit-derived beverages, particularly pomegranate juice. This study aimed to quantify the occurrence of 5-HMF and PAT in commercial reconstituted pomegranate juices and assess the associated dietary exposure risks. A total of 154 commercial samples, collected from a Turkish processing facility during the 2024–2025 production seasons, were analysed using high-performance liquid chromatography with diode-array detection. 5-HMF was detected in 152 samples (98.7%) at concentrations ranging from 1.03 to 10.79 mg/kg, with only two samples (1.3%) exceeding the critical threshold of 10 mg/kg. PAT was found in 57 samples (37.0%), with concentrations between 3.61 and 50.69 µg/kg, and only one sample (0.6%) exceeded the European Union maximum level established for fruit juices. Estimated mean daily intakes for adults and children ranged from 0.374 to 2.362 and 1.139 to 8.546 µg/kg bw/day for 5-HMF, and from 0.001 to 0.006 and 0.002 to 0.021 µg/kg bw/day for PAT, respectively. Risk characterisation based on hazard quotient values indicated that PAT exposure did not pose a significant health risk for either population group, highlighting the overall safety of the analysed products. Full article
(This article belongs to the Special Issue Chemical Approaches in Food Quality and Safety)
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