Isolation, Analysis, and Application of Characteristic Compounds from Natural Product and Synthesis of Their Analogue

Dear Colleagues,

Natural products such as agricultural, fishery and livestock products contain specific compounds that are beneficial to human health and play an important role through physiological activity when ingested. In modern society, extending the healthy lifespan has become an important social issue, and thus industry has taken a special interest in the commercialization of these compounds. To this end, economic separation and analysis of specific compounds are required; furthermore, it is necessary to pursue the production of high-added-value products through the useful transformation of specific compounds.

This Special Issue is focused on the analysis of characteristic compounds of natural products. Examples of such compounds are neutral lipids and specific fatty acids, phospholipids, anthocyanins, lignans, alkaloids, carotenoids, sterols, vitamins, minerals, etc. Topics to be covered will include quantitative analysis for determining the number of compounds contained in various natural products along with the development of analysis methods, comparison between these methods and their improvement in targeting these compounds.

Examples of such techniques include the isolation method for phospholipids contained in specific natural products, such as phosphatidyl choline and phosphatidyl ethanolamine, quantitative analysis using HPLC-ELSD, MS/MS or ³¹P-NMR and scaled-up isolation methods for industrial application.

Furthermore, it is possible to convert these specific compounds isolated from natural products or by already commercialized by enzymatic and chemical methods into industrially high-value-added forms (e.g., materials for mRNA vaccines). For this purpose, a conversion method is used, which can be commercialized along with separation, purification and identification methods from a reactant.

This Special Issue, “Isolation, Analysis, and Application of Characteristic Compounds from Natural Product and Synthesis of Their Analogue”, welcomes original research on:

1) Methods of isolation and analysis of characteristic compounds from natural products;

2) Methods of chemical or enzymatic reaction for modification of characteristic compounds with the downstream process (extraction, isolation, identification, characterization, application, etc.).

Dr. Ki-Teak Lee
Guest Editor

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