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Special Issue "A Themed Issue in Honor of Professor Raphael Mechoulam: The Father of Cannabinoid and Endocannabinoid Research"
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Bioactive Lipids".
Deadline for manuscript submissions: closed (1 October 2021) | Viewed by 33494
A printed edition of this Special Issue is available here.
Special Issue Editor
2. European Center for Brain Research, Santa Lucia Foundation IRCCS, Rome, Italy
Interests: arachidonate cascade; bioactive lipids; biomarkers; cell membranes; endocannabinoids; resolvins; signal transduction
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Special Issue Information
During the last 50 years, the relevance of cannabis (Cannabis sativa or Cannabis indica) ingredients, like the psychoactive Δ9-tetrahydrocannabinol (THC), cannabidiol, 120+ additional cannabinoids and 440+ non-cannabinoid compounds, for human health and disease has become apparent. Approximately 30 years later, the molecular reasons for the biological activity of these plant extracts were made clearer by the discovery of endocannabinoids, which are endogenous lipids able to bind to the same cannabinoid receptors activated by THC. Besides endocannabinoids, which include several N-acylethanolamines and acylesters, a complex array of receptors, metabolic enzymes, transporters (transmembrane, intracellular, and extracellular carriers) were also discovered, and together they form a so-called “endocannabinoid system,” which has been shown to finely tune the manifold biological activities of these lipid signals.
Both plant-derived cannabinoids and endocannabinoids were first discovered by the group of Dr. Raphael Mechoulam, who has just celebrated his 90th birthday, and clearly stands out as a giant of modern science. The many implications of his seminal work for chemistry, biochemistry, biology, pharmacology, and medicine are described in this Special Issue by the scientists who in the past 20 years have reached the highest recognition in the field of (endo)cannabinoid research, receiving the Mechoulam Award for their major contributions. I thank them for having accepted my invitation to be part of this honorary issue of Molecules, and Raphi for continuing to illuminate our field with his always inspiring investigations and new ideas.
Prof. Dr. Mauro Maccarrone
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Drug Discovery
- Human Health
- Lipid Biochemistry
- Signal Tranduction