Oxidative Stress as a Pharmacological Target for Medicinal Chemistry

Dear Colleagues,

It is well known that oxidative stress is one of the major factors contributing in the development of several chronic diseases such as cardiovascular disorders, cancer, different neurodegenerative diseases, diabetes, and aging. The reduction of oxidative stress-caused damages is essential in effective prevention and/or treatment of these types of pathologies. The impaired balance between the antioxidant defense mechanisms and the pro-oxidant processes can be restored either by increasing the former or decreasing the latter.

This Special Issue may cover all aspects of the oxidative stress-related research. Original research papers as well as review articles are welcomed on the synthesis, derivatization, extraction, purification, and structural analysis of possible new antioxidants, their biological evaluation, and mechanisms of action. Furthermore, studies of new exogenous or endogenous modulators of oxidative stress in different oxidative stress-related disease models are also welcomed.

Dr. Istvan Bak
Dr. Attila Kiss
Dr. Istvan Lekli
Guest Editors