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Special Issue "Selected Papers from the 6th International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-6)"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 30 April 2021.

Special Issue Editors

Prof. Dr. Nazim Sekeroglu
E-Mail Website
Guest Editor
Department of Food Engineering, Faculty of Engineering and Architecture, Kilis 7 Aralık University, 79000 Kilis, Turkey
Interests: from nature to fields; cultivation and processing of medicinal and aromatic plants (MAPs); good collection and agricultural practices of MAPs; from plant raw material to final products; good manufacturing practices and quality aspects; bioactivities of plant secondary metabolites
Special Issues and Collections in MDPI journals
Prof. Dr. Anake Kijjoa
E-Mail Website
Guest Editor
Departamento de Química, Instituto de Ciências Biomédicas de Abel Salazar and CIIMAR, Universidade do Porto, Rua Jorge de Viterbo Ferreira, nº228, 4050-313 Porto, Portugal
Interests: isolation, structure elucidation of bioactive compounds from terrestrial and marine organisms; secondary metabolites
Special Issues and Collections in MDPI journals
Prof. Dr. Sevgi Gezici
E-Mail Website
Guest Editor
Department of Molecular Biology & Genetics, Faculty of Science & Art, Kilis 7 Aralık University, 79000 Kilis, Turkey
Interests: human genetics; molecular biology of cancer; cancer genetics; apoptosis and signaling pathways; cancer proteomics; medical biology; medicinal and aromatic plants; bioactivities of plant secondary metabolites; in vivo and in vitro anticancer and antitumor research
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Increasing health concerns and limited medication treatments for incurable diseases in the modern medical system have led health professionals, and especially desperate patients, to turn to traditional medicinal formulas, especially medicinal plants and herbal medicines. Thus, the phytochemical aspects of medicinal and aromatic plants and their uses in  traditional medicine have aroused considerable interest among the scientists working in this field. Medicinal and aromatic plants (MAPs) and, to some extent, non-wood forest products (NWFPs) are important in many sectors such as food, beverage, pharmaceuticals, nutraceuticals, cosmeceuticals, perfumery, food additives, and self-care products. Recently, novel herbal products, super foods, herbal coffees, natural cosmetics, and many other herbal products have been rediscovered and their market size has increased considerably. Conservation of plant diversity, sustainable wild harvesting of medicinal and aromatic plants, good agricultural production, post-harvest technologies, good manufacturing processing of herbal products, their quality control under good laboratory practices, and legal issues surrounding these products for public health are the main priorities of governments around the world. Besides official efforts, non-governmental/non-profit organizations (NGOs/NPOs) are also working for these targets.

Following a very successful MESMAP-5, which was jointly organized with the 4th International Symposium on Pharmaceutical and Biomedical Sciences (ISPBS-5), in Cappadocia, Turkey, in April 2019, we are now organizing the Sixth International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-6), which will be held at Richmond Ephesus Resort Hotel in Selcuk (Ephesus), Izmir, TURKEY, during 15-17 October 2020. The MESMAP-6 scientific program covers all the aspects of MAPs and NWFPs including phytochemistry, phytopharmacology, pharmacognosy, herbal medicines, ethnobotany, plant biotechnology, agriculture, and forestry. Detailed topics for the conference can be found on the conference website: http://www.mesmap.com/.

This Special Issue of Molecules on “Selected Papers from the 6th International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-6)” welcomes submissions of previously unpublished manuscripts from original work on all the above aspects, including isolation, structure elucidation, and biological activity of plant secondary metabolites; pharmacological study of medicinal plants and traditional medicine formulae; efficacy of natural products; safety and regulations on natural products; and natural products used in cosmeceuticals, nutraceuticals, and veterinary medicine.

Please note that reports of known compounds from new plant sources will not generally be accepted unless they have relevant biological and pharmacological activities. Plant extracts used for in vitro and/or in vivo pharmacological studies must be characterized by analysis of their major constituents (e.g., HPLC fingerprints, HPLC-MS, GC-MS, or NMR analyses).

Finally, the organizing committee wishes to welcome participants from all continents to this important scientific gathering in Ephesus, Turkey, “A world cultural heritage in the extraordinary natural and historical setting of the world". Like the previous editions of MESMAP, we are sure that all participants will have the opportunity to share their knowledge, experience, and expertise at this scientific gathering. We also hope that no one will resist the beauty of the spring in Ephesus. The Editorial of this Special Issue plans to receive full paper submissions from 1 November 2020 to 31 January 2021. We wish you all the best, and we look forward to meeting you in Ephesus in October.

Prof. Dr. Nazim Sekeroglu
Prof. Dr. Anake Kijjoa
Prof. Dr. Sevgi Gezici
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (3 papers)

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Research

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Open AccessArticle
Phytochemical Profile, Antioxidant Activity, and Cytotoxicity Assessment of Tagetes erecta L. Flowers
Molecules 2021, 26(5), 1201; https://doi.org/10.3390/molecules26051201 - 24 Feb 2021
Viewed by 424
Abstract
Tagetes erecta L. is a popular ornamental plant of the Asteraceae family, which is widely cultivated not only for its decorative use, but also for the extraction of lutein. Besides carotenoid representatives, which have been extensively studied, other important classes of secondary metabolites [...] Read more.
Tagetes erecta L. is a popular ornamental plant of the Asteraceae family, which is widely cultivated not only for its decorative use, but also for the extraction of lutein. Besides carotenoid representatives, which have been extensively studied, other important classes of secondary metabolites present in the plant, such as polyphenols, could exhibit important biological activities. The phytochemical analysis of a methanolic extract obtained from T. erecta inflorescences was achieved using liquid chromatography–mass spectrometry (LC-MS) techniques. The extract was further subjected to a multistep purification process, which allowed the separation of different fractions. The total extract and its fractions contain several polyphenolic compounds, such as hydroxybenzoic and hydroxycinnamic acid derivatives, flavonols (especially quercetagetin glycosides), and several aglycons (e.g., quercetin, patuletin). One of the fractions, containing mostly quercetagitrin, was subjected to two different antioxidant assays (metal chelating activity and lipoxygenase inhibition) and to in vitro cytotoxicity assessment. Generally, the biological assays showed promising results for the investigated fraction compared to the initial extract. Given the encouraging outcome of the in vitro assays, further purification and structural analysis of compounds from T. erecta extracts, as well as further in vivo investigations are justified. Full article
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Open AccessArticle
Phytochemical Analysis and Habitat Suitability Mapping of Glycyrrhiza glabra L. Collected in the Hatay Region of Turkey
Molecules 2020, 25(23), 5529; https://doi.org/10.3390/molecules25235529 - 25 Nov 2020
Viewed by 507
Abstract
The growth and quality of licorice depend on various environmental factors, including the local climate and soil properties; therefore, its cultivation is often unsuccessful. The current study investigated the key factors that affect the contents of bioactive compounds of Glycyrrhiza glabra L. root [...] Read more.
The growth and quality of licorice depend on various environmental factors, including the local climate and soil properties; therefore, its cultivation is often unsuccessful. The current study investigated the key factors that affect the contents of bioactive compounds of Glycyrrhiza glabra L. root and estimated suitable growth zones from collection sites in the Hatay region of Turkey. The contents of three bioactive compounds (glycyrrhizic acid, glabridin, and liquiritin), soil factors (pH, soil bearing capacity, and moisture content), and geographical information (slope, aspect, curvature, elevation, and hillshade) were measured. Meteorological data (temperature and precipitation) were also obtained. An analysis of variance (ANOVA) and multivariate analysis of variance (MANOVA) were performed on the data. The soil bearing capacity, moisture content, slope, aspect, curvature, and elevation of the study area showed statistically significant effects on the glycyrrhizic acid and liquiritin contents. A habitat suitability zone map was generated using a GIS-based frequency ratio (FR) model with spatial correlations to the soil, topographical, and meteorological data. The final map categorized the study area into four zones: very high (15.14%), high (31.50%), moderate (40.25%), and low suitability (13.11%). High suitability zones are recommended for further investigation and future cultivation of G. glabra. Full article
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Review

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Open AccessReview
Natural Products from Medicinal Plants with Anti-Human Coronavirus Activities
Molecules 2021, 26(6), 1754; https://doi.org/10.3390/molecules26061754 - 21 Mar 2021
Viewed by 708
Abstract
Since the emergence of severe acute respiratory syndrome caused by coronavirus 2 (SARS-CoV-2) first reported in Wuhan, China in December 2019, COVID-19 has spread to all the continents at an unprecedented pace. This pandemic has caused not only hundreds of thousands of mortalities [...] Read more.
Since the emergence of severe acute respiratory syndrome caused by coronavirus 2 (SARS-CoV-2) first reported in Wuhan, China in December 2019, COVID-19 has spread to all the continents at an unprecedented pace. This pandemic has caused not only hundreds of thousands of mortalities but also a huge economic setback throughout the world. Therefore, the scientific communities around the world have focused on finding antiviral therapeutic agents to either fight or halt the spread of SARS-CoV-2. Since certain medicinal plants and herbal formulae have proved to be effective in treatment of similar viral infections such as those caused by SARS and Ebola, scientists have paid more attention to natural products for effective treatment of this devastating pandemic. This review summarizes studies and ethnobotanical information on plants and their constituents used for treatment of infections caused by viruses related to the coronavirus family. Herein, we provide a critical analysis of previous reports and how to exploit published data for the discovery of novel therapeutic leads to fight against COVID-19. Full article
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