Microneedle-Mediated Diagnosis and Therapeutics of Diseases
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 2625
Special Issue Editors
Interests: microneedles; microparticles; nanoparticles
Special Issues, Collections and Topics in MDPI journals
Interests: membrane-active peptides/peptidomimetics; smarted drug delivery system; microneedles; hydrogel; nanosheets; bioinspired materials; biomaterials
Special Issues, Collections and Topics in MDPI journals
Interests: dissolving microneedles for transdermal drug delivery; porous carriers for drug delivery; immunotherapy; phototherapy; nanomedicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Nowadays, microneedles (MNs) with micron-sized needles ranging from 100 to 1000 µm have been well-developed to pierce multiple biological barriers in a minimally invasive manner, achieving controlled-release drug delivery for therapy or extraction of tissue interstitial fluid for diagnosis. MNs could be used to deliver various agents, including small molecules, macromolecules, or a wide range of nanomedicines (e.g., polymeric nanoparticles, inorganic nanoparticles, and two-dimensional nanosheets), for the treatment of various diseases. By tailoring the drug release behavior and distribution, MNs could serve as a promising platform for the theragnostics of topical (e.g., skin diseases, oral diseases, cardiovascular diseases, and brain diseases) or systemic diseases (e.g., diabetes, contraception, and neurological disorders). In addition, the rational and personalized design of MNs provides improved pharmacokinetics, pharmacodynamics, and safety profiles to deliver fluorescent probes and/or therapeutics, making it an attractive alternative for future chemotherapy, phototherapy, immunotherapy, chemodynamic therapy, and combinatory therapies.
This Special Issue aims to highlight the recent advances in the development of smart microneedles for disease diagnosis and therapy. Original research papers, reviews, and mini-review papers are all welcome.
Dr. Tingting Peng
Dr. Chao Lu
Dr. Guilan Quan
Guest Editors
Manuscript Submission Information
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Keywords
- microneedle
- drug delivery
- diagnosis
- therapy
- diseases
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