Recent Advances in Microneedle-Mediated Drug Delivery, 2nd Edition
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 6213
Special Issue Editors
Interests: microneedles; pulmonary drug delivery; novel drug-delivery systems
Special Issues, Collections and Topics in MDPI journals
Interests: dissolving microneedles for transdermal drug delivery; porous carriers for drug delivery; immunotherapy; phototherapy; nanomedicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Microneedles (MNs) have become a new generation of topical delivery systems, which are revolutionizing the landscape of transdermal drug delivery. In general, MNs are micrometer-sized needles arranged orderly on a base, and their lengths usually range from 25 to 2000 μm. Research has proved that the MNs can penetrate the stratum corneum and create an array of temporary microchannels in the skin, which can significantly increase transdermal drug permeation. In addition, MNs are designed to penetrate into the viable epidermis and upper dermis, to avoid contact with the nerve fibers and blood vessels that reside primarily in the deep dermal layer, resulting in minimal pain and invasiveness. With great patient compliance and efficiency in drug delivery, MNs could offer unlimited potential for the transdermal delivery of various therapeutic agents such as small molecules, biological macromolecules, vaccines, and even nanoparticles.
The theme of this Special Issue deals with all aspects of microneedle-mediated drug-delivery systems including the design, fabrication, and characterization of microneedle formulations, and their use as strategies for the prevention or treatment of medical conditions such as cancer, infection, diabetes, and dermatological diseases and for vaccinations.
Dr. Xin Pan
Dr. Guilan Quan
Guest Editors
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Keywords
- transdermal drug delivery
- microneedle-mediated drug delivery
- dissolving microneedles
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Related Special Issue
- Recent Advances in Microneedle-Mediated Drug Delivery in Pharmaceutics (8 articles)