Special Issue "Dendrimers as Nanocarriers for Drug Delivery"
Deadline for manuscript submissions: 1 September 2019
Prof. Dr. Mire Zloh
UCL School of Pharmacy, 29/39 Brunswick Square, London, UK
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Interests: computer-aided molecular design; molecular dynamics; computational chemistry; protein–ligand interactions; protein–excipient interactions; formulation design; NMR spectroscopy; antimicrobial peptide modelling
Medicines development research strives to improve drug efficacy and effectiveness via the optimization of drug delivery to achieve controlled release at the target site. The use of nanocarriers can improve the bioavailability of drugs and, at the same time, circumvent problems associated with their off-target interactions. These novel delivery systems offer opportunities to expand the spectrum of biomedical applications of molecules with poor drug-like properties.
Dendrimers, branched polymers with their highly tunable three-dimensional structure and modifiable surface functionalities, are attractive systems for drug delivery due to the possibility to build multifunctional nanocarriers for the targeted and smart release of the active pharmaceutical ingredient. The structure of the dendrimers can be varied to accommodate different molecules and/or to target different tissues, while the choice of monomers, number of generations, and surface modifications can be guided by computational chemistry approaches. Exploiting this versatile molecular architecture can unlock almost unlimited potential applications of dendrimers for the treatment of many diseases.
This Special Issue aims to attract contributions covering all fields concerning the development of dendrimers as nanocarriers, including the rational design of novel dendrimers as delivery systems, their synthesis with challenges in characterization, and their biomedical applications.
Honorary Prof. Dr. Mire Zloh
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Drug delivery
- Drug encapsulation
- Drug targeting
- Dendrimer drug interactions
- Controlled release
- pH-responsive nanocarriers