Advances in Medicinal Chemistry for Age-Related Diseases
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 20
Special Issue Editor
Interests: medicinal chemistry; organic chemistry; chemical biology; drug discovery; drug delivery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Age-related diseases represent a growing global health concern as life expectancy increases worldwide. Conditions such as Alzheimer’s disease, Parkinson’s disease, cardiovascular disorders, type 2 diabetes, osteoporosis, and certain cancers are closely related to the aging process and often share common molecular and cellular pathways, including oxidative stress, inflammation, and mitochondrial dysfunction. Medicinal chemistry plays a pivotal role in identifying, designing, and optimizing small molecules and other therapeutic agents to target these complex mechanisms.
This Special Issue aims to highlight recent advances in medicinal chemistry that address the challenges of treating these complex diseases. Contributions may include the discovery of novel bioactive molecules, structure–activity relationship studies, the development of multitarget-directed ligands, novel strategies for improving drug selectivity and bioavailability, and insights from computational approaches.
We invite original research articles, reviews, communications and concept papers from both academia and industry that explore innovative strategies for the diagnosis and treatment of age-related conditions. This Special Issue seeks to bring together interdisciplinary efforts and collaborative research to provide a comprehensive overview of the latest findings in this broad field.
Dr. Maria João Matos
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- age-related diseases
- neurodegenerative diseases
- cardiovascular diseases
- bioactive molecules
- biomolecules
- synthesis
- computational studies
- medicinal chemistry
- chemical biology
- drug discovery
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