Cannabis, Hemp and Endocannabinoid System Modulation: Pharmacology, Toxicology and Therapeutic Advances
A Special Issue of Molecules (ISSN 1420-3049) belonging to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 May 2027 | Viewed by 348
Editors
Interests: cannabinoids; endocannabinoid system; cannabis and hemp extracts; metabolic disorders; metabolic dysfunction associated steatotic liver disease (MASLD); oxidative stress; inflammation; metabolic syndrome; nutraceuticals; pharmacology and toxicology of cannabinoids; experimental models of metabolic disease; translational research in cannabinoid biology and metabolic health
Special Issue Information
Dear Colleagues,
In recent years, cannabis, hemp, and cannabinoid-based compounds have attracted a great deal of scientific and clinical attention. Advances in analytical chemistry, pharmacology, molecular biology, and both preclinical and clinical research have improved our understanding of the endocannabinoid system (ECS), a key biological network essential for maintaining homeostasis that is involved in metabolic, inflammatory, immune, neurological, hepatic, and cardiovascular regulation. ECS dysregulation has been associated with multiple chronic conditions, and its targeted modulation (pharmacological or nutritional) has emerged as a promising strategy for the prevention and treatment of various diseases. Nevertheless, important challenges remain with regard to safety, toxicity, dose standardization, long-term effects, interactions among phytocannabinoids and terpenes, and the molecular mechanisms that regulate endogenous endocannabinoid pathways.
This Special Issue aims to gather high-quality contributions addressing the pharmacological, toxicological, and therapeutic potential of cannabis, cannabinoids and hemp, as well as methodological innovations and translational advances supporting evidence-based clinical applications. We welcome experimental studies and reviews and perspectives that present new approaches, emerging findings, and recent developments in the field.
Dr. María Eugenia Oliva
Dr. Laura Romina Caltana
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cannabis
- hemp
- cannabinoids
- endocannabinoid system
- ECS modulation
- phytocannabinoids
- terpenes
- pharmacology
- toxicology
- therapeutic applications
- metabolic disorders
- liver disease
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