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Analytical Methods for Toxics Determination Ⅱ

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 4797

Special Issue Editors


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Guest Editor
International Forensic Research Institute, Department of Chemistry and Biochemistry, Florida International University, Miami, FL, USA
Interests: chromatographic stationary phases; substrate-free solid-phase extraction sorbents; molecular imprinting technology; sorbents for environmental pollution remediation; miniaturized sample preparation devices; field deployable sample preparation technology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Chemistry, Jamia Millia Islamia (Central University), Jamia Nagar, New Delhi 110025, India
Interests: innovative extraction procedures and instrument configurations; bioactive compounds; characterization, fingerprints and method validation; HPLC

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Guest Editor
Department of Pharmacy, University “G. d\'Annunzio” of Chieti and Pescara, Chieti, Italy
Interests: innovative (micro)extraction procedures; hyphenated instrument configurations; bioactive compounds; characterization; fingerprints; method validation; HPLC; mass spectrometry; biological matrices; chromatography; analytical chemistry; sample preparation; green analytical methodologies
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Assistant Editor
Department of Pharmacy, University “G. d'Annunzio” of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy
Interests: sample preparation; biological matrices; bioanalysis; microextraction procedures; separation techniques; chromatography
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent decades, but especially in recent years, the rapid spread of toxic species has occurred in all matrices. Evidently, these contaminants, both of inorganic and organic origin, are very dangerous pollutants for human health, owing to their bioaccumulation and toxicity. They come from almost all human activities, such as, for example, industries, agriculture, vehicular traffic and urban heating.

Considering that, often, these species occur in various real matrices at extremely low concentrations, analytical methodologies must evidently show their possible application by verifying the correctness of all the steps: sampling, sample preparation, instrumental measurement and statistical data processing.

Another extremely important aspect concerns the fact that the development of new analytical methodologies, and the contemporary lack or inadequacy of regulations regarding the determination of toxic species in the most varied matrices, can obviously give to the legislator the possibility to update and improve the above-mentioned regulations.

This Special Issue aims to attract contributions on all aspects linked to the different analytical methods used for the determination of toxic species in the most varied matrices—food, environmental, forensic, biological, etc.—focusing particularly on the fundamental parameters of interest to set-up an analytical procedure, such as precision and trueness (that together give accuracy); the limits of detection and quantification; selectivity; and, especially, sensitivity.

This Special Issue is supported by the Sample Preparation Task Force and Network of the European Chemical Society Division of Analytical Chemistry (https://www.sampleprep.tuc.gr/en/home/).

Prof. Dr. Abuzar Kabir
Prof. Dr. Imran Ali
Prof. Dr. Marcello Locatelli
Prof. Dr. Dora Melucci
Dr. Angela Tartaglia
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Inorganic toxic species
  • Organic toxic species
  • Analytical methods
  • Chemometrics
  • Practical applications

Published Papers (2 papers)

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Research

17 pages, 3459 KiB  
Article
Antioxidant Activity Evaluation of FlexirubinType Pigment from Chryseobacterium artocarpi CECT 8497 and Related Docking Study
by Abeer Mogadem, Mohamed Ali Almamary, Naji Arafat Mahat, Khairunadwa Jemon, Wan Azlina Ahmad and Imran Ali
Molecules 2021, 26(4), 979; https://doi.org/10.3390/molecules26040979 - 12 Feb 2021
Cited by 10 | Viewed by 2164
Abstract
The current research is focused on studying the biological efficacy of flexirubin, a pigment extracted from Chryseobacterium artocarpi CECT 8497.Different methods such as DPPH, H2O2, NO, O2•−, OH, lipid peroxidation inhibition by FTC and [...] Read more.
The current research is focused on studying the biological efficacy of flexirubin, a pigment extracted from Chryseobacterium artocarpi CECT 8497.Different methods such as DPPH, H2O2, NO, O2•−, OH, lipid peroxidation inhibition by FTC and TBA, ferric reducing and ferrous chelating activity were carried out to evaluate the antioxidant activity of flexirubin. Molecular docking was also carried out, seeking the molecular interactions of flexirubin and a standard antioxidant compound with SOD enzyme to figure out the possible flexirubin activity mechanism. The new findings revealed that the highest level of flexirubin exhibited similar antioxidant activity as that of the standard compound according to the H2O2, OH, O2•−, FTC and TBA methods. On the other hand, flexirubin at the highest level has shown lower antioxidant activity than the positive control according to the DPPH and NO• and even much lower when measured by the FRAP method. Molecular docking showed that the interaction of flexirubin was in the binding cavity of the SOD enzyme and did not affect its metal-binding site. These results revealed that flexirubin has antioxidant properties and can be a useful therapeutic compound in preventing or treating free radical-related diseases. Full article
(This article belongs to the Special Issue Analytical Methods for Toxics Determination Ⅱ)
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9 pages, 741 KiB  
Article
Multi-Walled Carbon Nanotubes Solid-Phase Extraction and Capillary Electrophoresis Methods for the Analysis of 4-Cyanophenol and 3-Nitrophenol in Water
by Zeid A. ALOthman, Ahmad Yacine Badjah, Marcello Locatelli and Imran Ali
Molecules 2020, 25(17), 3893; https://doi.org/10.3390/molecules25173893 - 26 Aug 2020
Cited by 8 | Viewed by 1992
Abstract
Analysis of 4-cyanophenol and 3-nitrophenol was carried out using multi-walled carbon nanotubes-based solid-phase extraction (SPE) and capillary electrophoresis (CE) methods. Capillary electrophoresis was carried out with 18 kV voltage, 214 nm detection, and phosphate buffer (pH 7.0, 15 mM) as background electrolyte at [...] Read more.
Analysis of 4-cyanophenol and 3-nitrophenol was carried out using multi-walled carbon nanotubes-based solid-phase extraction (SPE) and capillary electrophoresis (CE) methods. Capillary electrophoresis was carried out with 18 kV voltage, 214 nm detection, and phosphate buffer (pH 7.0, 15 mM) as background electrolyte at 25 ± 1 °C temperature with 15.05 and 16.5 min migration times of 4-cyanophenol and 3-nitrophenol. The separation and resolution factors were 1.10 and 2.90. The optimized experimental conditions were 40 mg/L concentration, 1.0 g multi-walled carbon nanotubes (MWCNTs) per SPE cartridge, 5.0 mL/min flow rate of water, 0.1 mL flow rate of eluting solvent. The maximum recoveries were 91% and 98% at 0.1 mL/min flow rate of 4-cyanophenol and 3-nitrophenol. These methods were applied successfully for extraction and estimation of 4-cyanophenol and 3-nitrophenol in the municipal wastewater. The reported methods are reproducible, efficient, and practical for the estimation of these phenols in water. Full article
(This article belongs to the Special Issue Analytical Methods for Toxics Determination Ⅱ)
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