New Advances in Radiopharmaceutical Sciences
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 6639
Special Issue Editor
Interests: radiopharmaceutical sciences; radiolabeling chemistry; radiometals for medicinal purposes; PET tracers; dosimetry for individualized treatment-planning; nuclide production; automatization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The different steps of developing radiopharmaceuticals, from the basic idea to their final clinical application (and approval), represent the strongly interdisciplinary character of nuclear medicine.
Preclinical as well as clinical evaluation of any novel radiopharmaceutical (antibodies, peptides, small molecules) deals with all subjects related to the identification of new molecular targets and their specific utilization for efficient nuclear medical imaging and therapy options in a variety of medical conditions such as neurodegenerative or cardiovascular metabolic disorders, cancer or other immune-associated diseases. This includes in vitro and in vivo measurements and modeling of radiotracer binding, distribution and pharmacokinetics as well as dosimetry studies. Sophisticated investigations and advances in clinical research have increasingly opened up new attractive areas of application for radiopharmaceuticals. Examples are the imaging-based patient selection and their use as theranostic tool for a personalized treatment.
The core of the design of a radiopharmaceutical is the choice of the adequate radiochemistry, which includes the choice of the radionuclide due its chemical and physical properties, its production and purification, the choice of suitable labeling strategies and precursors, which takes the chemistry and pharmacokinetics of the target vector into account. All this finally leads to an optimized automated synthesis of pharmaceutical grade radiopharmaceuticals.
The editors of this Special Issue of Molecules welcome all contributions (communications, research papers and review articles) on new advances concerning the manifold facets of radiopharmaceuticals and their development.
Dr. Elisabeth Eppard
Guest Editor
Manuscript Submission Information
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Keywords
- radiopharmacy/radiopharmaceuticals
- radiochemistry
- radionuclide therapy
- theranostics
- PET
- SPECT
- radiolabeling techniques
- radionuclide production
- nuclear medicine
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