Heterocyclic Compounds in Drug Discovery and Their Medical Applications
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 496
Special Issue Editors
Interests: drug development; green chemistry; mechanochemistry; heterocycle synthesis; Alzheimer's disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Heterocyclic systems constitute one of the most relevant families of compounds in organic chemistry, which are widely represented in many fields of science and life. Thus, compounds containing a heterocyclic core are a cornerstone of activity and human life, since heterocyclic systems are a key scaffold for the synthesis of a number of natural products and several biomolecules. Furthermore, heterocyclic systems play a pivotal role in the development of new materials, in the agri-food industry, in food manufacturing, and of course are and will be essential structures in medical chemistry, to develop drugs and diagnostic devices.
Heterocyclic systems play a key role in human and animal health, since food is a natural source of these systems and due to their wide therapeutic and diagnostic applications. Heterocyclic systems are considered privileged structures in drug discovery programs because they are able to operate as a pharmacophore structure against one or more therapeutic targets, and as modulators of ADMET properties. On the other hand, the use of physico-chemical properties such as the luminescence of heterocyclic systems is an important diagnostic tool. Thus, in recent years, the duality of diagnostic and therapeutic approaches has resulted in the development of a growing field of theranostic systems, in which heterocyclic systems have an important function.
This Special Issue will present original research using heterocyclic systems to develop new therapeutic, diagnostic or theranostic agents.
Prof. Dr. Juan F. González
Dr. Irene Ortin Remon
Guest Editors
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Keywords
- heterocyclic
- therapeutic agents
- diagnostic agents
- theranostic agents
- medicinal chemistry
- drug discovery
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