Bioengineered Peptides and Proteins as Potential Therapeutic Agents

Dear Colleagues,

The forthcoming Special Issue of Molecules, entitled “Bioengineered Peptides and Proteins as Potential Therapeutic Agents”, explores the rapidly evolving field of bioengineered peptides and proteins, emphasizing their emerging role as innovative therapeutic agents. Recent advances in synthetic biology, protein engineering, and molecular modelling have enabled the synthesis of novel peptides and proteins with enhanced bioactivity, stability, and specificity. Moreover, machine learning and artificial intelligence have introduced powerful methodologies in the prediction of structure—function relationships and accelerated drug design and development.   

This Special Issue is open for the submission of original research articles, reviews and short communications that delve into the molecular engineering of peptides and proteins for therapeutic uses.  Some representative topics of interest include the following:

• Design and optimization of therapeutic peptides and proteins;
• Peptide–drug conjugates;
• Peptidomimetics;
• Protein scaffolds and platforms;
• Self-assembling peptides and proteins for tissue engineering and regenerative medicine;
• AI-driven modelling and computational design of peptides and proteins;
• Advanced strategies for targeted delivery of peptides and proteins;
• Improved bioavailability and controlled release of therapeutic peptides and proteins;
• Peptide-based biosensors.

Dr. Rigini M. Papi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.