Bacterial Infection and Antimicrobial Resistance
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".
Deadline for manuscript submissions: closed (31 May 2026) | Viewed by 1327
Editors
Interests: staphylococci; bacterial infection; antimicrobial resistance; biofilm; leprosy
Interests: Staphylococcus aureus; coagulase-negative staphylococci; antibiotic resistance; virulence factors; biofilm; molecular epidemiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Infections caused by pathogenic and opportunistic bacteria exert a profound impact on global public health. Bacterial infections constitute the second leading cause of mortality worldwide, a situation further exacerbated by the alarming rise in antimicrobial resistance (AMR)—a challenge that has become even more pressing in the aftermath of the COVID-19 pandemic.
Several bacterial species are recognized as major etiological agents of clinically significant infections, including Staphylococcus aureus (skin and soft tissue infections), Escherichia coli (urinary tract and kidney infections), Streptococcus pneumoniae (pneumonia and meningitis), Klebsiella pneumoniae (pneumonia and bloodstream infections), and Pseudomonas aeruginosa (pneumonia, urinary tract, and bloodstream infections). Other bacterial taxa, such as group B Streptococcus, Enterococcus spp., Neisseria spp., Haemophilus spp., Helicobacter pylori, and Chlamydia trachomatis, are less frequently implicated as primary causative agents of human infections.
The severity of infection is influenced not only by the virulence and pathogenic potential of the bacterial species but also by host-intrinsic factors, including immunocompromised status, extremes of age, and genetic background.
Antimicrobial resistance arises from a convergence of intrinsic genetic mechanisms and anthropogenic factors that accelerate its emergence and dissemination. Key drivers include the excessive and inappropriate use of antimicrobial agents in clinical and agricultural contexts, inadequate infection prevention and control practices, insufficient hygiene measures, and the circulation of substandard or falsified pharmaceuticals. At the molecular level, resistance develops through spontaneous mutations and horizontal gene transfer among bacterial populations. The selective pressure imposed by antimicrobial misuse further facilitates the survival and propagation of resistant strains, thereby intensifying the global AMR crisis.
This Special Issue seeks to showcase original research articles and comprehensive reviews that deepen current knowledge on bacterial infections and antimicrobial resistance, encompassing their emerging trends, molecular mechanisms, epidemiological patterns, and future perspectives for research, surveillance, and public health interventions.
Dr. Luiza Pinheiro-Hubinger-Stauffer
Prof. Dr. Maria de Lourdes Ribeiro de Souza da Cunha
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bacterial infections
- Staphylococcus
- Streptococcus
- Escherichia coli
- Klebsiella pneumoniae
- Pseudomonas aeruginosa
- antimicrobial resistance
- mutations
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