Microfluidics for Bioanalysis: From Sample Preparation to Integrated Detection
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".
Deadline for manuscript submissions: 25 June 2026 | Viewed by 1633
Special Issue Editor
Interests: biomicrofluidics; blood rheology; blood dynamics; lab-on-a-chip
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bio-samples provide clinical and significant information on the healthy status or disease progression. Blood flow in micron-sized capillary channels (i.e., microcirculation) is substantially determined by blood mechanical factors, including hematocrit, viscosity, aggregation, and deformability. These factors have also been regarded as clinically important biomarkers for screening or diagnosing patients’ diseases. Thus, consistent assessment of blood mechanical properties has been considered a vital issue in blood biophysics. More recently, microfluidics has been extensively employed to probe blood mechanical properties. When red blood cells are altered from a normal state to an abnormal physiological state, biophysical properties or morphology parameters (i.e., surface area, volume, or density) are varied significantly and heterogeneously. For early detection, a novel microfluidic platform or medical device needs to detect small variations or subpopulations in whole blood. This Special Issue welcomes manuscripts related to the following topics, but is not limited to them:
- Blood-on-a-chip for probing blood mechanical properties;
- Single-cell morphology analysis of bio-sample;
- Mathematical modeling of blood flow in micro-scale physics;
- Disposable microfluidic device for POCT test.
Prof. Dr. Yang Jun Kang
Guest Editor
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Keywords
- blood-on-a-chip for quantification of hemorheological properties
- single cell morphology analysis of bio-sample
- mathematical modeling under micro-scale physics
- disposable microfluidic device for POCT test
- experimental visualization technique under microfluidic platform
- microfluidic device for quantifying heterogeneity of red blood cells
- microfluidic device for handing or analyzing biofluids
- blood-on-a-chip
- disposable POCT device
- heterogeneity of RBCs
- on-chip detection of hemorheological properties of blood
- POCT device to evaluate RBCs’ flow properties
- microfluidic systems with integrated sensors for single-red-blood-cell analysis
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