Biodegradable Magnesium Alloys 2020

A special issue of Metals (ISSN 2075-4701). This special issue belongs to the section "Biobased and Biodegradable Metals".

Deadline for manuscript submissions: closed (31 August 2021) | Viewed by 3401

Special Issue Editor


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Guest Editor
Department of Engineering, University of Cambridge, Trumpington St, Cambridge CB2 1PZ, UK
Interests: metallic biomaterials; biodegradable metals; biocorrosion; coating and surface modifications; additive manufacturing; bone tissue engineering; magneto-mechanical actuation; material–tissue interactions; porous materials; hydrogels; vascularization

Special Issue Information

Dear Colleagues,

For more than a hundred years, magnesium and its alloys were investigated extensively for a variety of biomedical applications, such as orthopedic implants, cardiovascular stents, and tissue engineering scaffolds. The potential of magnesium and its alloys as a temporary device material exceeds that of other materials due to their unique advantages in terms of biocompatibility and biodegradability. For bone fixation, magnesium is considered a preferable structural material due to its mechanical strength, which is relatively similar to the typical strength of bones and the fact that it stimulates bone growth. Nevertheless, experiments have clearly shown that the corrosion degradation rates of magnesium and its alloys are too high, which results in premature loss of structural integrity of the device and the formation of hydrogen gas bubbles that can cause separation of tissues and, in rare cases, gas embolism. Those problems limit the use of those alloys in practice. This Special Issue aims to present the latest innovative strategies to overcome the current limitations. Topics include, but are not limited to, the development of new alloys, structural and surface modifications for enhanced corrosion resistance, coatings, osseointegration, and in vitro and in vivo biological responses.

Dr. Galit Katarivas Levy
Guest Editor

Manuscript Submission Information

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Keywords

  • Mg and Mg-based alloys
  • biocompatibility
  • biodegradable
  • bioabsorble
  • corrosion resistance
  • coatings
  • surface modification
  • mechanical properties
  • wear resistance
  • in vitro and in vivo response

Published Papers (1 paper)

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Research

13 pages, 6928 KiB  
Article
Stress Corrosion and Corrosion Fatigue of Biodegradable Mg-Zn-Nd-Y-Zr Alloy in In-Vitro Conditions
by Lilach Elkaiam, Orly Hakimi and Eli Aghion
Metals 2020, 10(6), 791; https://doi.org/10.3390/met10060791 - 14 Jun 2020
Cited by 15 | Viewed by 2907
Abstract
Mg alloys are attractive as a structural material for biodegradable implants due to their mechanical properties, biocompatibility and degradation capability in physiological environments. However, their accelerated corrosion degradation, coupled with their inherent sensitivity to stress corrosion, can cause premature failure and consequently loss [...] Read more.
Mg alloys are attractive as a structural material for biodegradable implants due to their mechanical properties, biocompatibility and degradation capability in physiological environments. However, their accelerated corrosion degradation, coupled with their inherent sensitivity to stress corrosion, can cause premature failure and consequently loss of mechanical integrity. This study aims to evaluate the potential of a Mg-5% Zn alloy with up to 3% Nd as an implant material in terms of stress corrosion performance in in vitro conditions. Stress corrosion behavior was evaluated under static loading conditions using slow strain rate testing (SSRT) analysis and under low cycle corrosion fatigue (LCCF). Both the SSRT analysis and LCCF testing were carried out in a simulated physiological environment in the form of a phosphate-buffered saline (PBS) solution. The obtained results indicate that the addition of up to 3% Nd to Mg-5% Zn alloy did not have any substantial influence on the stress corrosion susceptibility, beyond the inherent different mechanical properties of the tested alloys. This was attributed to the limited effect of the Nd on the passivation layer and due to the fact that the secondary phases produced by the Nd additions—W-phase (Mg3(Nd,Y)2Zn3) and T-phase (Mg4(Nd,Y)Zn2)—did not create any substantial micro-galvanic effect. Full article
(This article belongs to the Special Issue Biodegradable Magnesium Alloys 2020)
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