Animal and Cellular Models in Metabolomics Research

Dear Colleagues,

Metabolomics, an essential tool of modern biochemical research, is no longer solely a hypothesis-generating platform, but rather is extensively used in hypothesis testing studies. Progress in gene manipulation techniques allows the turning on and off of particular enzymatic functions in a cell- or tissue-specific manner. High-throughput cell culture and animal model studies are increasingly popular. While many metabolic questions can be answered under well-controlled cell culture conditions, the true test is the transition from the dish to the in vivo models.

We therefore invite research and review articles devoted to various aspects of cell and animal models used in metabolic studies. The focus of this Special Issue involves technical approaches and the translation from cell to animal metabolic models. The topics include but are not limited to the use of cell culture and animal models in the exploration of single cell metabolism, high-throughput metabolomics, and the use of stable isotope tracers for metabolic flux analysis. Studies using genetic manipulations or in vivo dietary and pharmacological interventions are particularly welcome. Studies applying in vitro/in vivo imaging of metabolites with the use of DNP-NMR and MRI are highly anticipated. Finally, protocols describing experimental guidelines are also welcome.

The Special Issue is open for submission now. A proper extension may be granted, please kindly let us know in advance. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website.

Dr. Michal Ciborowski
Dr. Joanna Godzien
Dr. Stanislaw Deja
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.