Proteomics and Metabolomics in Human Health and Disease
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Advances in Metabolomics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 12
Special Issue Editors
Interests: proteomics; metabolomics; lipidomics; interactomics; bioinformatics; mass spectrometry; metabolism; mitochondria; single-cell omics; PTMs
Special Issues, Collections and Topics in MDPI journals
Interests: inherited metabolic disorders; metabolomics; newborn screening; proteomics; protein-protein interaction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Over the past two decades, the omics revolution has significantly advanced our understanding of human health and disease. Each omics discipline has developed into a specialized field, offering powerful insights into the complex molecular networks that underlie biological functions and dysfunctions.
Proteomics and metabolomics show the ability to capture the dynamic biochemical landscape. Proteomics involves the large-scale study of protein expression and modifications to disclose pathological processes, while metabolomics focuses on small molecules and lipids, providing a real-time snapshot of metabolic activities and cellular phenotypes. Together, these approaches deliver a detailed molecular fingerprint that can reveal subtle, yet clinically significant, changes associated with disease onset, progression, or treatment response. Moreover, the integration of multiple omics data types has emerged as a transformative approach in biomedical research, enabling a more comprehensive exploration of disease mechanisms and the discovery of novel diagnostic and therapeutic targets.
This Special Issue invites contributions that apply proteomics and metabolomics to biomedical research, particularly those addressing disease-related questions through experimental innovation or computational integration. This collection will contribute to a more precise, system-level understanding of health and disease, with wide-ranging applications in both basic science and personalized medicine.
Dr. Michele Costanzo
Prof. Dr. Margherita Ruoppolo
Guest Editors
Manuscript Submission Information
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Keywords
- proteomics
- metabolomics
- lipidomics
- multi-omics
- disease mechanisms
- machine learning
- omics integrations
- artificial intelligence
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