Bioactive Metabolites from Natural Sources (2nd Edition)

Dear Colleagues,

This Issue is dedicated to studies investigating compounds derived from nature. Nature is the best source of bioactive metabolites (BAMs), and knowledge about different classes of metabolites is constantly increasing. Organisms such as bacteria, algae, plants, and insects use their metabolites for their own benefit, but BAMs can often be beneficial for other organisms. BAMs are represented by primary and secondary metabolites, including amino acids, fatty acids, peptides, phytohormones, sugars, phenolics, terpenoids, and alkaloids. Synthetic molecules based on biomolecules are an additional useful source for the accelerated production of BAM-like compounds with increased efficiency. Molecular mechanisms and their regulation are of interest in terms of defining developmental, abiotic, and biotic factors that influence the level and activity of BAMs. Biotechnological approaches for increasing BAM production in an environmentally friendly fashion assist in furthering practical applications in agriculture, food quality, and human health.

This Special Issue invites you to the share latest advances, answering questions about various aspects of BAMs: What BAMs are produced in nature—different classes, evolution? What do we know about their mechanisms of action? Why they are useful for the organisms that synthesize them? How could they be useful by other organisms? How can we regulate their production in vitro and in vivo? Studies highlighting additional interesting aspects of BAM application will also be considered.

Dr. Miroslava Zhiponova
Dr. Zhenya P. Yordanova
Guest Editors

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