Clinical Advances and Challenges in the Treatment of Malocclusions and Temporomandibular Disorders

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Dentistry and Oral Health".

Deadline for manuscript submissions: 25 October 2026 | Viewed by 1391

Special Issue Editors


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Guest Editor
Dental School, Vita-Salute San Raffaele University, 20132 Milan, Italy
Interests: orthodontics; temporomandibular disorders; oral hygiene; growing subjects; digital orthodontics; functional orthodontic appliances; digital dentistry; clear aligners
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Dental School, Vita-Salute San Raffaele University, 20132 Milan, Italy
Interests: interceptive orthodontics; oral hygiene; functional orthodontic appliances; orthodontic materials; temporomandibular disorders; digital orthodontics; digital dentistry; clear aligners
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
1. Dental School, Vita-Salute San Raffaele University, 20132 Milan, Italy
2. Department of Dentistry, IRCCS San Raffaele Hospital, 20132 Milan, Italy
3. Department of Clinical Medicine, Public Health, Life and Environmental Sciences (MeSVA), University of L’Aquila, 24100 L’Aquila, Italy
Interests: orthodontics; temporomandibular disorders; oral hygiene; growing subjects; digital orthodontics; functional orthodontic appliances; digital dentistry; clear aligners

Special Issue Information

Dear Colleagues,

In recent decades, the dentistry field has experienced significant development, driven by rapid technological innovation and the widespread implementation of digital workflows. These developments have improved diagnostic accuracy, treatment efficiency, and clinician–patient communication, while also providing new opportunities to change the way orthodontic patients or those affected by temporomandibular disorders are viewed and treated. Digital monitoring systems, clear aligner therapy, mandibular kinematic analysis, guided placement of temporary anchorage devices, and multidisciplinary digitally assisted prosthetic rehabilitations have expanded treatment possibilities and enhanced the management of complex clinical conditions.

Moreover, the availability of large digital datasets has facilitated advanced analytical methods, supporting a more evidence-based and patient-centred clinical decision-making process. Artificial intelligence is also becoming increasingly widespread, bringing with it the possibility of simplifying the steps of our already well-validated protocols. It is therefore necessary to give importance and visibility to these innovations, while also validating their actual reliability.

This Special Issue aims to present current and emerging technologies in TMDs and orthodontics, encouraging the submission of original research, reviews and systematic reviews, so that the growth of innovation does not lead to mere simplification, but rather to greater precision in our field.

Dr. Alessandro Nota
Prof. Dr. Simona Tecco
Guest Editors

Dr. Laura Pittari
Guest Editor Assistant

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Keywords

  • TMD
  • orthodontics
  • digital dentistry
  • mandibular kinematics

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Published Papers (2 papers)

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Research

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13 pages, 490 KB  
Article
Childhood Obesity and Craniofacial Growth: A Cross-Sectional Orthodontic Cephalometric Study
by Sorana Maria Bucur, Dorin Ioan Cocoș, Cristian Doru Olteanu, Mioara Decusară, Mariana Păcurar and Eugen Silviu Bud
Medicina 2026, 62(5), 884; https://doi.org/10.3390/medicina62050884 - 5 May 2026
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Abstract
Background and Objectives: Childhood obesity is a major global health concern and is increasingly recognized as a factor influencing skeletal development. Emerging evidence suggests that excess adiposity may alter craniofacial growth patterns, with potential implications for orthodontic diagnosis and treatment planning. However, [...] Read more.
Background and Objectives: Childhood obesity is a major global health concern and is increasingly recognized as a factor influencing skeletal development. Emerging evidence suggests that excess adiposity may alter craniofacial growth patterns, with potential implications for orthodontic diagnosis and treatment planning. However, the extent to which obesity affects craniofacial morphology in growing individuals remains incompletely understood. This study aims to evaluate the association between body mass index (BMI) and craniofacial morphology in children and adolescents using selected sagittal and linear parameters, and to assess the independent effects of age and sex. Materials and Methods: This cross-sectional orthodontic study included 130 subjects aged ≤ 19 years. Anthropometric measurements were recorded, and BMI was used to classify participants as normal weight, overweight, or obese. Standardized lateral cephalometric radiographs were analyzed using skeletal and soft-tissue parameters. Statistical analyses included normality testing, one-way ANOVA with post hoc comparisons, and multivariate modeling. Results: Obesity was significantly associated with increased sagittal skeletal dimensions. Mandibular body length, mandibular unit length, SNB angle, and maxillary unit length demonstrated progressive increases across BMI categories (p < 0.05). In contrast, vertical growth parameters showed no significant differences. Soft-tissue analysis revealed reduced facial convexity and lower facial height ratios in obese subjects. Age was strongly associated with increases in linear jaw dimensions, whereas sex differences were limited primarily to skeletal size rather than morphological relationships. Conclusions: Childhood obesity is associated with enhanced sagittal craniofacial growth, particularly involving mandibular structures, while vertical skeletal patterns remain largely unaffected. These findings highlight the importance of incorporating BMI assessment into orthodontic evaluation and suggest that obesity may influence growth timing, facial morphology, and airway-related risk factors. Full article
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16 pages, 547 KB  
Systematic Review
Permanent Canine Impaction: A Systematic Review of Incidence, Distribution, and Etiology
by Marina Antoneta Pop, Sorana Maria Bucur and Anca Porumb
Medicina 2026, 62(4), 681; https://doi.org/10.3390/medicina62040681 - 2 Apr 2026
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Abstract
Background and Objectives: Tooth impaction is a common developmental dental anomaly characterized by the failure of eruption within the expected physiological timeframe. Permanent canines represent the second most frequently impacted teeth after third molars and may lead to functional, esthetic, and orthodontic [...] Read more.
Background and Objectives: Tooth impaction is a common developmental dental anomaly characterized by the failure of eruption within the expected physiological timeframe. Permanent canines represent the second most frequently impacted teeth after third molars and may lead to functional, esthetic, and orthodontic complications. This systematic review aimed to synthesize current evidence regarding the incidence, anatomical distribution, etiological determinants, and diagnostic evaluation of permanent canine impaction. Materials and Methods: A systematic literature search was conducted in PubMed, PubMed Central, and ScienceDirect for studies published between December 2009 and December 2025. Studies reporting prevalence data, anatomical positioning, etiological factors, or imaging characteristics of permanent canine impaction were included. Study selection followed PRISMA 2020 guidelines, and 31 studies were included in the qualitative synthesis. Two independent reviewers screened titles, abstracts, and full texts. Methodological quality was assessed using the Joanna Briggs Institute Critical Appraisal Tools. Results: Thirty-one studies met the inclusion criteria and were included in the qualitative synthesis. The reported prevalence of maxillary canine impaction ranged from 0.97% to 7.10%, while mandibular impaction occurred less frequently. Palatal displacement represented the most common positional pattern. Major etiological factors included retained deciduous canines, dental arch constriction, supernumerary teeth, odontomas, and genetic anomalies such as lateral incisor agenesis. Cone-Beam Computed Tomography (CBCT) demonstrated superior diagnostic accuracy compared with panoramic radiography. Conclusions: Permanent canine impaction is a multifactorial condition predominantly influenced by local anatomical and environmental factors, with genetic predisposition acting as a secondary contributor. Early diagnosis and appropriate imaging assessment are essential to prevent complications such as root resorption and to optimize treatment outcomes. Full article
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