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Therapeutic Advances in Craniofacial Disorders and Orthodontics in Growing and Adult Population

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: 30 September 2025 | Viewed by 1459

Special Issue Editors


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Guest Editor
Dental School, Vita-Salute San Raffaele University, 20132 Milan, Italy
Interests: orthodontics; temporomandibular disorders; oral hygiene; growing subjects; digital orthodontics; functional orthodontic appliances; digital dentistry
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Dental School, Vita-Salute San Raffaele University, 20132 Milan, Italy
Interests: interceptive orthodontics; oral hygiene; functional orthodontic appliances; orthodontic materials; temporomandibular disorders; digital orthodontics; digital dentistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recent years have seen a huge development i the advances in the management of craniomandibular disorders and orthodontic treatment both in adult and growing patients. In particular, there has been a massive increase in the use of digital technologies in these fields.

These advances allow for improved diagnosis, treatment efficiency, and communication between the patient and the clinician. Also, for research purposes, digital data have allowed new perspectives in data analysis and in the study of craniofacial growth. Intraoral scanners, digital monitoring technologies, artificial intelligence, digital treatment planning, clear aligners, mandibular kinematic analysis, guided placement of miniscrews, and multidisciplinary approaches to digital prosthetic rehabilitations are only some of the examples. These technologies are becoming part of our daily practice and should be considered as there is a continuous outbreak of new solutions, with clinicians needing scientific studies able to prove their efficacy and trustworthiness.

The aim of the present Special Issue is to shed light on the new technologies in this field, promoting the production of relevant scientific literature with research articles, original reviews, or high-quality case reports on new techniques or clinical solutions.

Dr. Alessandro Nota
Prof. Dr. Simona Tecco
Guest Editors

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Keywords

  • clear aligners
  • occlusal splints
  • temporomandibular disorders
  • craniomandibular disorders
  • digital dentistry
  • digital orthodontics
  • digital planning
  • artificial intelligence
  • miniscrews
  • digital analysis
  • craniofacial growth

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Published Papers (2 papers)

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10 pages, 1200 KiB  
Article
Comparison of Frontal Sinus Dimensions with Different Skeletal Classes and Vertical Patterns: A Retrospective Study
by Alessandro Nota, Iuliia Kashtelianska, Francesco Manfredi Monticciolo, Laura Pittari, Simona Tecco and Attilio Castaldo
Healthcare 2025, 13(11), 1310; https://doi.org/10.3390/healthcare13111310 - 31 May 2025
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Abstract
Background: The aim of this work is to compare the size of the frontal sinus and the different skeletal classes and divergence patterns of the subjects. Methods: This study retrospectively includes lateral radiographs performed on a total of 200 adults (78 M, 122 [...] Read more.
Background: The aim of this work is to compare the size of the frontal sinus and the different skeletal classes and divergence patterns of the subjects. Methods: This study retrospectively includes lateral radiographs performed on a total of 200 adults (78 M, 122 F; mean age 29.2 ± 8.0 years). Subject inclusion criteria were an age of 18–45 years, presence of both frontal sinuses, and good general health with no hormonal system disorders that may affect the growth and pneumatization of the frontal sinuses. Four different parameters of the frontal sinus were evaluated: length, width, perimeter, and area. In order to calculate the variables inherent to the sagittal and vertical skeletal pattern, two independent nominal variables were considered: skeletal class (ANB°) and mandibular divergence (SN^MP°). Results: The statistical analysis showed that there is a statistically significant difference between the frontal sinus dimension and the three skeletal classes. Subjects in group 3 presented significantly higher mean dimensional values. In the analysis of sinus size variables with skeletal divergence, significant results were found for the width value, which resulted in higher average values in group c. Conclusions: The present study shows a statistically significant difference in frontal sinus size among different skeletal classes and divergence patterns. This result suggests that, in future studies, it should be analyzed whether the dimensional analysis of the frontal sinus could be associated with skeletal class III malocclusion. Full article
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28 pages, 2405 KiB  
Systematic Review
Systematic Review and Meta-Analysis of Electromyography Potential to Discriminate Muscular or Articular Temporomandibular Disorders and Healthy Patients
by Maria Isabella Federici, Francesca Di Pasquale, Chiara Valenti, Alessandro Nanussi, Ornella Tulli, Maddalena Coniglio, Stefano Eramo, Lorella Marinucci and Stefano Pagano
Healthcare 2025, 13(5), 466; https://doi.org/10.3390/healthcare13050466 - 21 Feb 2025
Cited by 1 | Viewed by 831
Abstract
Background/Objectives: New devices such as surface electromyography (sEMG) have been proposed to support traditional gnathological examination and diagnostic protocols. The aim of this study is to investigate whether sEMG can be considered a diagnostic instrument to discriminate between healthy subjects and patients [...] Read more.
Background/Objectives: New devices such as surface electromyography (sEMG) have been proposed to support traditional gnathological examination and diagnostic protocols. The aim of this study is to investigate whether sEMG can be considered a diagnostic instrument to discriminate between healthy subjects and patients with temporomandibular disorders (TMDs) of an articular or muscular nature. Methods: A systematic review was conducted according to PRISMA guidelines using literature searches of MEDLINE (via PubMed), Scopus, and Web of Science. Inclusion criteria: recent clinical studies (≤10 years) in English or Italian, involving electromyography in TMD diagnosis, with a control group of healthy patients. Data considered to be homogenous were subjected to meta-analysis (95% confidence interval [CI]; α = 0.05). Hedge g was calculated because all variables were continuous. Articles meeting the inclusion criteria were checked for further consideration, and relevant data were collected into two tables. In total, 18 studies were included after full-text reading. Meta-analyses were carried out for the static impact index (IMP), percentage overlapping coefficient (POC), and torque coefficient, and dynamic Symmetrical Mastication Index (SMI). Results: Patients with TMD had lower values in all parameters except IMP. sEMG registered a reduction in masseter activity, lower chewing efficiency, and an increase in fatigue during contractions in TMD patients. Conclusions: sEMG is not reliable to distinguish healthy from TMD patients, but despite the limitations related to the high variability in the studies (type of electromyography, static or dynamic tests, and population characteristics), the sEMG results are reliable considering the POC and SMI parameters, encouraging more in-depth studies for a predictable clinical practice. Patients with TMD had lower values in the dynamic index SMI and in static indexes POC and torque coefficient, except IMP. EMG might performs better if employed in muscle forms. Full article
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